The Effect of the Second Messenger c-di-GMP on Bacterial Chemotaxis in Escherichia coli. [PDF]
Appl Environ Microbiol, 2022 Liu X, Zhang C, Zhang R, Yuan J.
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
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A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4. [PDF]
Biochem JOrzechowski M +5 more
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Light dependent synthesis of a nucleotide second messenger controls the motility of a spirochete bacterium. [PDF]
Sci Rep, 2022 Xu J +5 more
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Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems
Advanced NanoBiomed Research, EarlyView.Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai +6 more
wiley +1 more source
Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc pathway. [PDF]
Sci Rep, 2023 Cardona-Acosta AM +5 more
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Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
A Second Role for the Second Messenger Cyclic-di-GMP in E. coli: Arresting Cell Growth by Altering Metabolic Flow. [PDF]
mBio, 2023 Hwang Y, Harshey RM.
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cAMP-related second messenger pathways modulate hearing function in <i>Aedes aegypti</i> mosquitoes. [PDF]
iScienceXu YYJ +9 more
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Multivalent Ligand-Nanoparticle Conjugates Amplify Reactive Oxygen Species Second Messenger Generation and Enhance Epidermal Growth Factor Receptor Phosphorylation. [PDF]
Bioconjug Chem, 2022 Zhang S, Ouyang T, Reinhard BM.
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