Results 141 to 150 of about 6,888,408 (247)

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Tale of Twin Bifunctional Second Messenger (p)ppGpp Synthetases and Their Function in Mycobacteria. [PDF]

ACS Omega, 2023
Sinha SK, Rs N, Devarakonda Y, Rathi A, Reddy Regatti P, Batra S, Syal K.   +6 more
europepmc   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

MESSENGER for Teachers

, 2010
MESSENGER is a scientific investigation - by spacecraft - of the planet Mercury. The name comes from "MErcury Surface, Space ENvironment, GEochemistry, and Ranging," highlighting the project's broad range of scientific goals.

core  

Osmotic stress responses and the biology of the second messenger c-di-AMP in Streptomyces. [PDF]

Microlife, 2023
Bhowmick S, Shenouda ML, Tschowri N.
europepmc   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Editorial: Roles of the first and second messengers in reproduction

Frontiers in Endocrinology
Xiaoning Zhang, Rujun Ma
doaj   +1 more source

Differential second messenger signaling via dopamine neurons bidirectionally regulates memory retention. [PDF]

Proc Natl Acad Sci U S A, 2023
Takakura M, Lam YH, Nakagawa R, Ng MY, Hu X, Bhargava P, Alia AG, Gu Y, Wang Z, Ota T, Kimura Y, Morimoto N, Osakada F, Lee AY, Leung D, Miyashita T, Du J, Okuno H, Hirano Y.   +18 more
europepmc   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Control of light-dependent behaviour in cyanobacteria by the second messenger cyclic di-GMP. [PDF]

Microlife, 2023
Enomoto G, Wallner T, Wilde A.
europepmc   +1 more source