Results 241 to 250 of about 130,287 (295)
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Opioid receptor-coupled second messenger systems
Life Sciences, 1991Although pharmacological data provide strong evidence for different types of opioid receptors (e.g., mu, delta, and kappa), they share many common properties in their ability to couple to second messenger systems. All opioid receptor types are coupled to G-proteins, since agonist binding is diminished by guanine nucleotides and agonist-stimulated ...
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Autoradiographic analysis of second-messenger systems in the gerbil brain
Brain Research Bulletin, 1988Quantitative in-vitro autoradiographic study was performed to localize two prominent second-messenger systems (the adenylate cyclase and phosphoinositide systems) in the normal gerbil brain. [3H] Forskolin and [3H] phorbol 12, 13-dibutyrate (PDBu) were used to identify the regional distribution of adenylate cyclase and protein kinase C, respectively ...
Kortaro Tanaka +2 more
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Beyond receptors: Multiple second-messenger systems in brain
Annals of Neurology, 1987AbstractSecond‐messenger systems play a major role in mediating neurotransmitter actions. In recent years our understanding of the organization and function of two prominent second‐messenger systems has progressed rapidly—the adenylate cyclase and phosphoinositide systems. Guanosine triphosphate–binding proteins, which are especially abundant in brain,
Paul F Worley +2 more
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Second Messenger Systems Underlying Plasticity at the Neuromuscular Junction
International Review of Neurobiology, 1999 Publisher Summary The Drosophila neuromuscular junction provides elegant significant experimental model to study signal transduction pathways that mediate synaptic plasticity because of its accessibility to electrophysiological techniques, morphological analyses, and pharmacological and genetic manipulations at identifiable synapses.
F, Hannan, Y, Zhong
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Adrenoceptors and Their Second Messenger Systems
Journal of Neurochemistry, 1993Ross A D Bathgate, Roger J Summers
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Opioid Regulation of Second Messenger Systems
Analgesia (Elmsford, N Y ), 1998Sandra C Roerig
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Journal of Cerebral Blood Flow and Metabolism, 1991 Alterations of the second-messenger systems, adenylate cyclase (AC) and protein kinase C (PKC), and local cerebral blood flow (1CBF) were evaluated during experimental cerebral ischemia in gerbils employing a quantitative autoradiographic method, which ...
Kortaro Tanaka +2 more
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The Second-Messenger System for Peptide Hormones
Hospital Practice, 1989There are three major hormone classes--peptide, steroid, and the newly defined growth factors--each with its own system for signal transduction in the cell. Two interdependent theses are proposed for the peptide hormone: that incoming signal transduction requires coupling to a G protein in a second-messenger pathway, and that second-messenger ...
R M, Hanley, A L, Steiner
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