Thymus, undernutrition, and infection: Approaching cellular and molecular interactions
Frontiers in Nutrition, 2022 Undernutrition remains a major issue in global health. Low protein-energy consumption, results in stunting, wasting and/or underweight, three deleterious forms of malnutrition that affect roughly 200 million children under the age of five years ...
Wilson Savino +14 more
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Cyto- and histoarchitectonics of the chicken spleen in the post-vaccination period
Ukrainian Journal of Veterinary and Agricultural Sciences, 2022 One of the main functions of the spleen is participation in many immunological processes, protecting the body from various harmful agents. It is a secondary organ of lymphopoiesis and the only organ of immunogenesis, which provides immune control of ...
T. S. Budnik, S. V. Guralska
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Organoid Models of Lymphoid Tissues
OrganoidsLymphoid organs are critical for organizing the development of the immune system, generating immune tolerance, and orchestrating the adaptive immune response to foreign antigens.
Ania Bogoslowski +3 more
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Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays
Frontiers in Immunology, 2020 By preserving cell viability and three-dimensional localization, organotypic culture stands out among the newest frontiers of cell culture. It has been successfully employed for the study of diseases among which neoplasias, where tumoral cells take ...
Francesca Finetti +9 more
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Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity [PDF]
Immunological Reviews, 2012 SummarySecondary lymphoid organs (SLOs), including lymph nodes, Peyer's patches, and the spleen, have evolved to bring cells of the immune system together. In these collaborative environments, lymphocytes scan the surfaces of antigen‐presenting cells for cognate antigens, while moving along stromal networks.
Deepali, Malhotra +2 more
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Regulation of adaptive immune responses by guiding cell movements in the spleen
Frontiers in Microbiology, 2015 The spleen combines the innate and adaptive immune systems in a uniquely organized way. The excision of spleen will induce many complications, especially the increased susceptibility to infections.
lintao ezhao +3 more
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Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham +7 more
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Clusterin is a potential lymphotoxin beta receptor target that is upregulated and accumulates in germinal centers of mouse spleen during immune response. [PDF]
PLoS ONE, 2014 Clusterin is a multifunctional protein that participates in tissue remodeling, apoptosis, lipid transport, complement-mediated cell lysis and serves as an extracellular chaperone. The role of clusterin in cancer and neurodegeneration has been extensively
Marina A Afanasyeva +5 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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BAFF induces CXCR5 expression during B cell differentiation in bone marrow
Biochemistry and Biophysics Reports, 2023 B cell activating factor (BAFF) plays an important role in antibody production through differentiation and maturation of B cells mainly in secondary lymphoid organs.
Hajime Koizumi +3 more
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