Results 11 to 20 of about 54,493 (255)

Tumor metabolic and secondary lymphoid organ metabolic markers on 18F-fludeoxyglucose positron emission tomography predict prognosis of immune checkpoint inhibitors in advanced lung cancer [PDF]

Frontiers in Immunology, 2022
Menglin Bai, Jinming Yu
exaly   +2 more sources

Organ-Specific Migration License (OSML) theory: a novel paradigm for spatiotemporal regulation and intervention of cross-organ immune cell migration in tumor immune responses [PDF]

Cell Communication and Signaling
The efficacy of antitumor immune responses depends not only on the activation and effector function of local immune cells but also on the dynamic interplay between the tumor microenvironment and systemic immunity.
Jiaming Cui, Jingru Han, Yang Dai, Shengqiang Li, Xinyu Wang, Ting Ge, Guixin He, Juyue Zhou, Li Yang, Yuanyuan Tian, Yingying Xie, Lefan Liu, Jinghui Du, Wentao Li, Jianchun Yu   +14 more
doaj   +2 more sources

Neutrophils in secondary lymphoid organs [PDF]

Immunology, 2021
AbstractNeutrophils are traditionally considered short‐lived, circulating innate immune cells that are rapidly recruited to sites of inflammation in response to infectious and inflammatory stimuli. Neutrophils efficiently internalize, kill or entrap pathogens, but their effector molecules may cause collateral tissue damage.
Lok, Laurence SC, Clatworthy, Menna R
openaire   +2 more sources

A rare case of synchronous mucosa-associated lymphoid tissue (MALT) lymphoma involving bilateral breasts and subcutaneous tissues

Radiology Case Reports, 2022
Marginal zone lymphoma of mucosa-associated lymphoid tissue is a B-cell lymphoma which arises in extranodal sites, most commonly the stomach. Involvement of the breast is very rare.
Cecile D Moliva Anendaga, MD, Madhavi Raghu, MD, Jaime L Szarmach, MD, Seema Bakhru, MD, Francis T Flaherty, MD, Gilda Boroumand, MD   +5 more
doaj   +1 more source

Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells

Frontiers in Immunology, 2022
Regulatory T cells in non-lymphoid tissues are not only critical for maintaining self-tolerance, but are also important for promoting organ homeostasis and tissue repair.
Kathrin L. Braband, Kathrin L. Braband, Tamara Kaufmann, Tamara Kaufmann, Stefan Floess, Mangge Zou, Jochen Huehn, Jochen Huehn, Michael Delacher, Michael Delacher   +9 more
doaj   +1 more source

Protective fibroblastic niches in secondary lymphoid organs

Journal of Experimental Medicine, 2023
Fibroblastic reticular cells (FRCs) are specialized fibroblasts of secondary lymphoid organs that provide the structural foundation of the tissue. Moreover, FRCs guide immune cells to dedicated microenvironmental niches where they provide lymphocytes and myeloid cells with homeostatic growth and differentiation factors.
Angelina De Martin, Yves Stanossek, Natalia Barbara Pikor, Burkhard Ludewig   +3 more
openaire   +3 more sources

Emergence and Evolution of Secondary Lymphoid Organs [PDF]

Annual Review of Cell and Developmental Biology, 2016
For effective adaptive immunity to foreign antigens (Ag), secondary lymphoid organs (SLO) provide the confined environment in which Ag-restricted lymphocytes, with very low precursor frequencies, interact with Ag on Ag-presenting cells (APC). The spleen is the primordial SLO, arising in conjunction with adaptive immunity in early jawed vertebrates. The
Harold R, Neely, Martin F, Flajnik
openaire   +2 more sources

In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response

Cells, 2021
Germinal centers (GCs) are transient structures in the secondary lymphoid organs, where B cells undergo affinity maturation to produce high affinity memory and plasma cells.
Theinmozhi Arulraj, Sebastian C. Binder, Michael Meyer-Hermann   +2 more
doaj   +1 more source

Recent Progress of Tertiary Lymphoid Structure in Prognosis and Immunotherapy of Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2023
Lung cancer is the leading cause of cancer death, and non-small cell lung cancer (NSCLC) accounts for 85%. Immunotherapy has significantly improved the clinical prognosis of patients with NSCLC. However, because of the complexity and heterogeneousness of
Ying LIU, Lei XIONG, Ruoxue CAI, Yue CHEN, Jinjun YE, Bo SHEN, Guoren ZHOU   +6 more
doaj   +1 more source

Stroma cell priming in enteric lymphoid organ morphogenesis

Frontiers in Immunology, 2012
The lymphoid system is equipped with a network of specialized platforms located at strategic sites, which grant strict immune-surveillance and efficient immune responses.
Manuela eFerreira, Rita Gomes Domingues, Henrique eVeiga-Fernandes   +2 more
doaj   +1 more source