Results 161 to 170 of about 38,664 (219)

Recent advances towards BACE1 drug discovery and therapeutics design. [PDF]

RSC Med Chem
Imran S, Patel M, Noroozifar M, Kerman K.   +3 more
europepmc   +1 more source

Increasing expression of presenilin 1, β-catenin, and p-PTEN and its regulatory roles on cell invasion in gastric cancer. [PDF]

World J Gastrointest Oncol
Lin X, Lin GF, Gu FT, Li YL.
europepmc   +1 more source

γ-Secretase inhibitors and modulators

Biochimica Et Biophysica Acta - Biomembranes, 2013
γ-Secretase is a fascinating, multi-subunit, intramembrane cleaving protease that is now being considered as a therapeutic target for a number of diseases. Potent, orally bioavailable γ-secretase inhibitors (GSIs) have been developed and tested in humans with Alzheimer's disease (AD) and cancer.
Todd E Golde, Edward H Koo, Kevin M Felsenstein   +2 more
exaly   +3 more sources