Results 31 to 40 of about 34,649 (253)
Frontiers in Cellular Neuroscience, 2017 Postnatal development of the cerebellum is critical for its intact function such as motor coordination and has been implicated in the pathogenesis of psychiatric disorders.
Lei Wang, Li Zhang, Billy K. C. Chow
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The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach [PDF]
, 2013 The calcitonin gene-related peptide (CGRP) receptor is a complex of a calcitonin receptor-like receptor (CLR), which is a family B G-protein-coupled receptor (GPCR) and receptor activity modifying protein 1.
Alex C. Conner +13 more
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Structural characterization of outer membrane components of the type IV pili system in pathogenic Neisseria. [PDF]
PLoS ONE, 2011 Structures of the type IV pili secretin complexes from Neisseria gonorrhoeae and Neisseria meningitidis, embedded in outer membranes were investigated by transmission electron microscopy. Single particle averaging revealed additional domains not observed
Samta Jain +7 more
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Veterinary Sciences, 2022 Magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) have emerged as non-invasive diagnostic techniques for the diagnosis of pancreatic and pancreatic duct disorders in humans.
Chiara Briola
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Secretin facilitates GABA transmission in the cerebellum [PDF]
, 2001 Secretin was the first hormone discovered in human history, and yet, its function as a neuropeptide has been overlooked in the past. The recent discovery of the potential use of secretin in treating autistic patients, together with the conflicting ...
Chan, SCY +5 more
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Assembly mechanism of a Tad secretion system secretin-pilotin complex
Nature Communications, 2023 The bacterial Tight adherence Secretion System (TadSS) assembles surface pili that drive cell adherence, biofilm formation and bacterial predation. The structure and mechanism of the TadSS is mostly unknown.
Matteo Tassinari +3 more
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Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?
Cells, 2021 Cholangiocarcinoma is a lethal disease with scarce response to current systemic therapy. The rare occurrence and large heterogeneity of this cancer, together with poor knowledge of its molecular mechanisms, are elements contributing to the difficulties ...
Leonardo Baiocchi +11 more
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Type IV Pilus Secretins Have Extracellular C Termini
mBio, 2015 Type IV pili (T4Ps) are surface appendages used by Gram-negative and Gram-positive pathogens for motility and attachment to epithelial surfaces. In Gram-negative bacteria, such as the important pediatric pathogen enteropathogenic Escherichia coli (EPEC),
Joshua A. Lieberman +4 more
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Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development
Biomedicines, 2022 Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying.
Anja Klussmeier +4 more
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The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]
, 2014 G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin +8 more
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