Results 21 to 30 of about 11,220 (181)
Type IV Pilus Secretins Have Extracellular C Termini
mBio, 2015 Type IV pili (T4Ps) are surface appendages used by Gram-negative and Gram-positive pathogens for motility and attachment to epithelial surfaces. In Gram-negative bacteria, such as the important pediatric pathogen enteropathogenic Escherichia coli (EPEC),
Joshua A. Lieberman +4 more
doaj +1 more source
Veterinary Sciences, 2022 Magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) have emerged as non-invasive diagnostic techniques for the diagnosis of pancreatic and pancreatic duct disorders in humans.
Chiara Briola
doaj +1 more source
Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?
Cells, 2021 Cholangiocarcinoma is a lethal disease with scarce response to current systemic therapy. The rare occurrence and large heterogeneity of this cancer, together with poor knowledge of its molecular mechanisms, are elements contributing to the difficulties ...
Leonardo Baiocchi +11 more
doaj +1 more source
Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development
Biomedicines, 2022 Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying.
Anja Klussmeier +4 more
doaj +1 more source
mBio, 2017 Sophisticated nanomachines are used by bacteria for protein secretion. In Gram-negative bacteria, the type 2 secretion system (T2SS) is composed of a pseudopilus assembly platform in the inner membrane and a secretin complex in the outer membrane.
Iain D. Hay +2 more
doaj +1 more source
The serendipitous origin of chordate secretin peptide family members
BMC Evolutionary Biology, 2010 Background The secretin family is a pleotropic group of brain-gut peptides with affinity for class 2 G-protein coupled receptors (secretin family GPCRs) proposed to have emerged early in the metazoan radiation via gene or genome duplications.
Gomes Ana S +3 more
doaj +1 more source
Structure, 2013 Secretins are major constituents of bacterial type III secretion systems (T3SS). In this issue of Structure, Kowal and colleagues report on the cryo-EM structure of the native YscC secretin from Yersinia, revealing its internal symmetry and mode of length adaptation.
openaire +2 more sources
eLife, 2021 The ability to produce outer membrane projections in the form of tubular membrane extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among diderm bacteria.
Mohammed Kaplan +17 more
doaj +1 more source
The mechanism for polar localization of the type IVa pilus machine in Myxococcus xanthus
mBio, 2023 Type IVa pili (T4aP) are important for bacterial motility, adhesion, biofilm formation, and virulence. This versatility is based on their cycles of extension, adhesion, and retraction.
Marco Herfurth +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source