Results 31 to 40 of about 15,697 (209)

Type IV Pilus Secretins Have Extracellular C Termini

open access: yesmBio, 2015
Type IV pili (T4Ps) are surface appendages used by Gram-negative and Gram-positive pathogens for motility and attachment to epithelial surfaces. In Gram-negative bacteria, such as the important pediatric pathogen enteropathogenic Escherichia coli (EPEC),
Joshua A. Lieberman   +4 more
doaj   +1 more source

Magnetic Resonance Imaging and Magnetic Resonance Imaging Cholangiopancreatography of the Pancreas in Small Animals

open access: yesVeterinary Sciences, 2022
Magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) have emerged as non-invasive diagnostic techniques for the diagnosis of pancreatic and pancreatic duct disorders in humans.
Chiara Briola
doaj   +1 more source

Structural and Functional Insights into the Pilotin-Secretin Complex of the Type II Secretion System [PDF]

open access: yes, 2012
PMCID: PMC3276575This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Rehman Saima   +25 more
core   +1 more source

Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?

open access: yesCells, 2021
Cholangiocarcinoma is a lethal disease with scarce response to current systemic therapy. The rare occurrence and large heterogeneity of this cancer, together with poor knowledge of its molecular mechanisms, are elements contributing to the difficulties ...
Leonardo Baiocchi   +11 more
doaj   +1 more source

Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development

open access: yesBiomedicines, 2022
Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying.
Anja Klussmeier   +4 more
doaj   +1 more source

Structure determination of membrane-located complexes: Aquaporin 8 and YscC secretin [PDF]

open access: yes, 2011
A biological membrane is key to the life of a cell. In all living cells a biological membrane separates a inner life and an outer environment. Plasma membrane has many functions such as responding to external signals and transmitting them into the cell,
Kowal, Julia
core   +1 more source

Structural Basis of Type 2 Secretion System Engagement between the Inner and Outer Bacterial Membranes

open access: yesmBio, 2017
Sophisticated nanomachines are used by bacteria for protein secretion. In Gram-negative bacteria, the type 2 secretion system (T2SS) is composed of a pseudopilus assembly platform in the inner membrane and a secretin complex in the outer membrane.
Iain D. Hay   +2 more
doaj   +1 more source

Secrets of a Secretin [PDF]

open access: yesStructure, 2013
Secretins are major constituents of bacterial type III secretion systems (T3SS). In this issue of Structure, Kowal and colleagues report on the cryo-EM structure of the native YscC secretin from Yersinia, revealing its internal symmetry and mode of length adaptation.
openaire   +2 more sources

Effect of Intraduodenal Bile and Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Vasoactive Intestinal Polypeptide and Somatostatin in Man [PDF]

open access: yes, 1994
Intraduodenal (i.d.) application of bile or Na-taurodeoxycholate (TDC) dose dependently enhances basal exocrine pancreatic secretion. The hydrokinetic effect is mediated at least in part by secretin.
Teufel, Johannes   +3 more
core   +1 more source

The serendipitous origin of chordate secretin peptide family members

open access: yesBMC Evolutionary Biology, 2010
Background The secretin family is a pleotropic group of brain-gut peptides with affinity for class 2 G-protein coupled receptors (secretin family GPCRs) proposed to have emerged early in the metazoan radiation via gene or genome duplications.
Gomes Ana S   +3 more
doaj   +1 more source

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