Results 31 to 40 of about 11,202 (179)

Psp Stress Response Proteins Form a Complex with Mislocalized Secretins in the Yersinia enterocolitica Cytoplasmic Membrane

mBio, 2017
The bacterial phage shock protein system (Psp) is a conserved extracytoplasmic stress response that is essential for the virulence of some pathogens, including Yersinia enterocolitica.
Disha Srivastava, Amal Moumene, Josué Flores-Kim, Andrew J. Darwin   +3 more
doaj   +1 more source

Magnetic Resonance Imaging and Magnetic Resonance Imaging Cholangiopancreatography of the Pancreas in Small Animals

Veterinary Sciences, 2022
Magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) have emerged as non-invasive diagnostic techniques for the diagnosis of pancreatic and pancreatic duct disorders in humans.
Chiara Briola
doaj   +1 more source

Assembly mechanism of a Tad secretion system secretin-pilotin complex

Nature Communications, 2023
The bacterial Tight adherence Secretion System (TadSS) assembles surface pili that drive cell adherence, biofilm formation and bacterial predation. The structure and mechanism of the TadSS is mostly unknown.
Matteo Tassinari, Marta Rudzite, Alain Filloux, Harry H. Low   +3 more
doaj   +1 more source

Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?

Cells, 2021
Cholangiocarcinoma is a lethal disease with scarce response to current systemic therapy. The rare occurrence and large heterogeneity of this cancer, together with poor knowledge of its molecular mechanisms, are elements contributing to the difficulties ...
Leonardo Baiocchi, Ilaria Lenci, Martina Milana, Lindsey Kennedy, Keisaku Sato, Wenjun Zhang, Burcin Ekser, Ludovica Ceci, Vik Meadows, Shannon Glaser, Gianfranco Alpini, Heather Francis   +11 more
doaj   +1 more source

Type IV Pilus Secretins Have Extracellular C Termini

mBio, 2015
Type IV pili (T4Ps) are surface appendages used by Gram-negative and Gram-positive pathogens for motility and attachment to epithelial surfaces. In Gram-negative bacteria, such as the important pediatric pathogen enteropathogenic Escherichia coli (EPEC),
Joshua A. Lieberman, Courtney D. Petro, Stefani Thomas, Austin Yang, Michael S. Donnenberg   +4 more
doaj   +1 more source

Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development

Biomedicines, 2022
Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying.
Anja Klussmeier, Stefan Aurich, Lars Niederstadt, Bertram Wiedenmann, Carsten Grötzinger   +4 more
doaj   +1 more source

Structural Basis of Type 2 Secretion System Engagement between the Inner and Outer Bacterial Membranes

mBio, 2017
Sophisticated nanomachines are used by bacteria for protein secretion. In Gram-negative bacteria, the type 2 secretion system (T2SS) is composed of a pseudopilus assembly platform in the inner membrane and a secretin complex in the outer membrane.
Iain D. Hay, Matthew J. Belousoff, Trevor Lithgow   +2 more
doaj   +1 more source

Secrets of a Secretin [PDF]

Structure, 2013
Secretins are major constituents of bacterial type III secretion systems (T3SS). In this issue of Structure, Kowal and colleagues report on the cryo-EM structure of the native YscC secretin from Yersinia, revealing its internal symmetry and mode of length adaptation.
openaire   +2 more sources

The serendipitous origin of chordate secretin peptide family members

BMC Evolutionary Biology, 2010
Background The secretin family is a pleotropic group of brain-gut peptides with affinity for class 2 G-protein coupled receptors (secretin family GPCRs) proposed to have emerged early in the metazoan radiation via gene or genome duplications.
Gomes Ana S, Vieira Florbela A, Cardoso João CR, Power Deborah M   +3 more
doaj   +1 more source

In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography

eLife, 2021
The ability to produce outer membrane projections in the form of tubular membrane extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among diderm bacteria.
Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R Wood, Catherine M Oikonomou, William J Nicolas, Poorna Subramanian, Lori A Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J Dobro, Yongtao Zhu, Mark J McBride, Ariane Briegel, Carrie L Shaffer, Grant J Jensen   +17 more
doaj   +1 more source