Results 61 to 70 of about 34,649 (253)

Effect of Oral Administration of Intact Casein on Gastrointestinal Hormone Secretion and Pancreatic α-Amylase Activity in Korean Native Steer [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2013
Three Korean native steers (779±24 kg) fitted with duodenal cannulas were used in a 3×3 Latin square design to investigate the influence of oral administration of soluble proteins, intact casein (IC) and acid hydrolyzed casein (AHC), on gastrointestinal ...
S. B. Lee   +9 more
doaj   +1 more source

Imaging and 3D reconstruction of membrane protein complexes by cryo-electron microscopy and single particle analysis [PDF]

open access: yes, 2006
Cryo-electron microscopy (cryo-EM) in combination with single particle image processing and volume reconstruction is a powerful technology to obtain medium-resolution structures of large protein complexes, which are extremely difficult to crystallize and ...
Gregorini, Marco
core   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

Secretin-stimulated MR cholangiopancreatography: spectrum of findings in pancreatic diseases

open access: yesInsights into Imaging, 2016
MR cholangiopancreatography (MRCP) is an imaging technique that has evolved over the past 2 decades and that continues to have a fundamental role in the non-invasive detection of morphologic features of the pancreatic ducts.
P. Boraschi   +3 more
semanticscholar   +1 more source

Enhancing Quality of Life of Proximal Gastrectomy: A Comprehensive Review of Anastomotic Innovations and Challenges

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background In recent years, the incidence of early upper gastric cancer has increased, leading to a wider adoption of proximal gastrectomy (PG) as a possible treatment option. PG is preferred over total gastrectomy (TG) due to its superior postoperative nutritional status and improved surgical safety.
Linchuan Li   +6 more
wiley   +1 more source

Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]

open access: yes, 2013
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico   +6 more
core   +1 more source

Involvement of Secretin in the Control of Cell Survival and Synaptic Plasticity in the Central Nervous System

open access: yesFrontiers in Neuroscience, 2020
With emerging evidence showing a wide distribution of secretin (SCT) and its receptor (SCTR) in the central nervous system (CNS), the putative neuropeptide role of SCT has become more appreciated since the disruption of SCT/SCTR axis affects various ...
Lei Wang, Li Zhang
doaj   +1 more source

Effects of a Secretin Receptor Antagonist on Cerebellar Learning [PDF]

open access: yes, 2016
Eyeblink conditioning (EBC) is an important procedure used to understand the neuronal plasticity that occurs with learning and memory. Delay EBC requires a brainstem-cerebellar circuit while the role of the cerebellum in trace EBC is not as well ...
Kather, Josefina M
core   +1 more source

Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings   +6 more
wiley   +1 more source

Secretin-dependent signals in the ventromedial hypothalamus regulate energy metabolism and bone homeostasis in mice

open access: yesNature Communications
Secretin, though originally discovered as a gut-derived hormone, is recently found to be abundantly expressed in the ventromedial hypothalamus, from which the central neural system controls satiety, energy metabolism, and bone homeostasis.
Fengwei Zhang   +10 more
doaj   +1 more source

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