Results 101 to 110 of about 2,802,374 (388)

A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria [PDF]

, 2020
Predator-prey interactions play important roles in the cycling of marine organic matter. Here we show that a Gram-negative bacterium isolated from marine sediments (Pseudoalteromonas sp.
Chen, Xiu-Lan, Chen, Yin, Ding, Haitao, Li, Chun-Yang, Lidbury, Ian, McMinn, Andrew, Su, Hai-Nan, Tang, Bai-Lu, Wang, Lei, Wang, Min, Wang, Peng, Yang, Jie, Yu, Yang, Zhang, Xi-Ying, Zhang, Yu-Zhong, Zhao, Hui-Lin, Zhong, Shuai   +16 more
core   +2 more sources

Type V Secretion Systems: An Overview of Passenger Domain Functions

Frontiers in Microbiology, 2019
Bacteria secrete proteins for different purposes such as communication, virulence functions, adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria.
Ina Meuskens, Athanasios Saragliadis, J. C. Leo, D. Linke   +3 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

The secretion and retraction processes of pollination drops of ancient Platycladus orientalis and their response to different pollen types

Frontiers in Plant Science
IntroductionThe pollination drop (PD) is an important ovular secretion that occurs during the pollination stage in gymnosperms.MethodsIn this study, ancient Platycladus orientalis trees near the Mausoleum of the Yellow Emperor were selected to ...
Wei Zhou, Liyan Gong, Xiaobing Wang, Nawen Li, Xin Zhang, Jianjun Liu   +5 more
doaj   +1 more source

Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. [PDF]

, 2020
Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and many human disorders, including pathological tissue fibrosis in major organs.
Bai, Meirong, Barbosa, Guilherme Oliveira, Chen, Andrew, Kornberg, Thomas B, Li, Hao, Luo, Shuo, Ma, Dengke K, Sheppard, Dean, Tsukui, Tatsuya, Wang, Bingying, Wang, Xin, Wei, Yuehua, Zhang, Zhe   +12 more
core   +1 more source

Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharides. [PDF]

, 1978
The effect of the common lipid moiety of bacterial LPS on secretion from washed human platelets has been studied. The lipid A-rich LPS of S. minnesota R595 and a lipid A preparation both potentiated platelet serotonin secretion in response to IgG ...
Ginsberg, MH, Henson, PM
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Role of Phospholipases in Fungal Fitness, Pathogenicity and Drug Development- Lessons from Cryptococcus neoformans

Frontiers in Microbiology, 2010
Many pathogenic microbes, including many fungi, produce phospholipases which facilitate survival of the pathogen in vivo, invasion and dissemination throughout the host, expression of virulence traits and evasion of host immune defense mechanisms.
Julianne eDjordjevic
doaj   +1 more source

Role of metal-dependent regulation of ESX-3 secretion in intracellular survival of Mycobacterium tuberculosis [PDF]

, 2016
More people die every year from Mycobacterium tuberculosis infection than from infection by any other bacterial pathogen. Type VII secretion systems (T7SS) are used by both environmental and pathogenic mycobacteria to secrete proteins across their ...
Philips, Jennifer A, Portal-Celhay, Cynthia, Raynowska, Jenelle, Thompson, Victor, Tinaztepe, Emir, Wei, Jun-Rong   +5 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source