Results 191 to 200 of about 61,645 (272)

Wharton's jelly mesenchymal stem cell-secretome enhances skin rejuvenation via ApoA4 and SERPINH1. [PDF]

Regen Ther
Lee NE, Hwang JI, Bang CY, Kim EH, Bang OY.   +4 more
europepmc   +1 more source

B‐Cell Differentiation of Human Hematopoietic Progenitors Is Efficiently Supported by Wharton Jelly‐Derived Mesenchymal Stem Cells

European Journal of Immunology, Volume 56, Issue 4, April 2026.
Wharton's jelly‐derived mesenchymal stromal cells isolated from umbilical cord were used to recreate a human stromal environment for B‐cell development in vitro. In co‐culture, CD34+ hematopoietic progenitors from bone marrow or cord blood differentiated into mature IgM‐expressing B cells by day 11, while the Nalm‐16 B‐ALL cell line showed rapid IgM ...
Louison Collet, Hakim Ouled‐Haddou, Hussein Ghamlouch, Walaa Darwiche, Cathy Gomila, Brigitte Gubler, Loïc Garcon, Delphine Lebon, Jean‐Pierre Marolleau   +8 more
wiley   +1 more source

Profiling the secretome: maternal obesity impacts redox and adipogenic signaling during neonatal mesenchymal stem cell adipogenesis. [PDF]

Stem Cells
Bellalta S, Pinheiro-Machado E, Casanello P, Faas M, Plösch T.   +4 more
europepmc   +1 more source

Development of Anti‐Inflammatory Extracellular Vesicles by Surface Expression of Syndecan‐4

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT The biological functions of extracellular vesicles (EVs) depend on their cellular source. Further, different subpopulations of EVs from the same cells carry different cargo, but differences in their biological functions are less understood. We here identify a very small EV subpopulation released by HEK293F cells (miniEVs).
Lijuan Yu, Markus Bergqvist, Kyong‐Su Park, Cecilia Lässer, Jan Lötvall   +4 more
wiley   +1 more source

Cigarette Smoke Extract Alters the Inflammatory Secretome of Osteoarthritis‐Affected Synovium Increasing Joint Tissue Oxidative Stress in an Indirect Co‐Culture Model

Journal of Orthopaedic Research, Volume 44, Issue 4, April 2026.
ABSTRACT Dysregulation of synovial homeostasis has been implicated in the pathophysiology of osteoarthritis (OA), but the effects that cigarette smoking has on OA‐affected synovium have yet to be studied. To further the knowledge on how cigarette smoke alters OA progression, we investigated the direct effects of cigarette smoke extract (CSE) on ...
Emily Sawvell DiNicola, Andrea Vera Martinez, Brian C. Burnikel, Jeremy J. Mercuri   +3 more
wiley   +1 more source

Secretome as a novel regenerative strategy for atopic dermatitis: a comprehensive review. [PDF]

Stem Cell Res Ther
Subramaniam P, Shafiee MN, Fadilah NIM, Fauzi MB, Maarof M.   +4 more
europepmc   +1 more source

Modulatory Effects of Folic Acid and Dental Pulp Stem Cell‐Derived Exosomes on Gene Expression in a Periodontal Injury Model

Natural Sciences, Volume 6, Issue 2, April 2026.
Dental pulp stem cellderived exosomes and folic acid are evaluated for their effects on gene expression in an in‐vitro periodontal injury model. Human gingival fibroblasts subjected to oxidative and mechanical injury are treated with folic acid, exosomes, or their combination.
Saghar Zarei, Mostafa Montazeri, Nader Tanideh, Shahrokh Zare, Mahintaj Dara   +4 more
wiley   +1 more source

Expression of BMP-2, OPG, RANKL And Number of Osteoblasts After Application of Bovine Amniotic Membrane and Secretome Umbilical Cord in Wistar Rats. [PDF]

Nanotheranostics
Setiawatie EM, Bargowo L, Supandi SK, Negoro VP, Y P A FDA, K A EL, Agusta R, Baharuddin NA.   +7 more
europepmc   +1 more source

Towards a Novel Biocontrol Strategy: High Performance of Optimised Cell Wall‐Degrading Enzymes Secreted by Escovopsis primorosea LBM 277

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Escovopsis primorosea LBM 277 efficiently produced proteases, β‐1,3‐glucanases and chitinases under submerged fermentation using Leucoagaricus gongylophorus cell walls and Mandels complex. RSM‐BBD optimization significantly increased enzyme activity. The enzymatic cocktail remained stable for 30 days at room temperature and pH 4–6, aligning with the ...
Marcela Paola Barengo, Natalia Soledad Amerio, Gustavo Ángel Bich, Pedro Darío Zapata, María Lorena Castrillo   +4 more
wiley   +1 more source

SHED secretome hydrogel combined with α-mangostin for periodontal bone regeneration: In vivo study. [PDF]

J Oral Biol Craniofac Res
Aljunaid MA, Ridwan RD, Budi HS, Yuliati, Qaid HR, Mahendra RD, Riveira CM, Aqrabi AN, Putranto AF, Al-Ghazaly F, Al-Kawri OM.   +10 more
europepmc   +1 more source