Results 201 to 210 of about 62,112 (253)

Identification of miR‐150‐5p in Human Amniotic Membrane Mesenchymal Cell‐Derived Extracellular Vesicles as a Novel Mechanism Driving Cardioprotection

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Human amniotic membrane mesenchymal stem cells (hAMSCs) provide significant cardioprotection following myocardial ischemia/reperfusion injury. They improve cardiac function and reduce fibrosis by modulating the MIAT/miR‐150‐5p/HOXA4 signalling axis.
Nunzio Alcharani, Laura Tesoro, Javier Díez‐Mata, José Luis Zamorano, Marta Saura, Maite Iglesias, Carlos Zaragoza   +6 more
wiley   +1 more source

Deciphering Stiffness-Driven Changes in Colorectal Cancer by Proteomics. [PDF]

Mol Cell Proteomics
Cresens C, Montero-Calle A, Solís-Fernández G, Shaghaghi B, Gerrits L, Aytekin S, Kouwer PHJ, Barderas R, Rocha S.   +8 more
europepmc   +1 more source

FNDC4 and FNDC5 Attenuate SARS‐CoV‐2 S1‐Induced Inflammatory Responses in Human Adipose Tissue

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
In obesity, reduced FNDC4 and FNDC5 amplify SARS‐CoV‐2 S1–driven inflammation in visceral adipose tissue. These adipo‐myokines limit adipocyte–macrophage inflammatory signalling, suggesting a protective role against viral‐induced adipose tissue dysfunction.
Gabriela Neira, Julia Hernández‐Castañeda, Victoria Catalán, Sara Becerril, Marina Martín, Víctor Valentí, Rafael Moncada, Camilo Silva, Javier Gómez‐Ambrosi, Javier Escalada, Gema Frühbeck, Amaia Rodríguez   +11 more
wiley   +1 more source

Mesenchymal Stem Cell Secretome for Cardiac Regeneration: Opportunity for Cell-Free Therapy. [PDF]

Int J Mol Sci
Piotrowska P, Kraskiewicz H, Klimczak A.
europepmc   +1 more source

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini, Lei Bao, Krishan D. Chhiba, Jing Li, Yulu Wang, Haley Gainer, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Fei Li Kuang, Kyle T. Amber   +10 more
wiley   +1 more source

A Degradomic Landscape of Proteolytic Remodeling in Melanoma Lung Metastasis. [PDF]

J Proteome Res
Alves Martins Nogueira CE, Olímpio F, Salardani M, Barcick U, Fonseca LR, Aimbire F, Lima Jedlicka LD, Loures FV, Capelo LP, Lima V, Monteiro de Oliveira T, Barros BCSC, Serrano SMT, Zelanis A.   +13 more
europepmc   +1 more source

The Secretome Derived From Serum‐Free Media of SHED‐MSCs Can Modulate THP‐1‐Derived Macrophage Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Although culturing cells in serum‐free or low‐serum media may lead to reduced cell proliferation, it is crucial to minimise the presence of foreign proteins and other impurities that could compromise the validity of experimental findings on immunomodulation.
Azadeh Mohammad‐Hasani, Saeed Mohammadi, Mohsen Saeidi, Ali Fallah, Ayyoob Khosravi   +4 more
wiley   +1 more source

The PPARβ/Delta-Induced Mesenchymal Stromal Cell Secretome Has Cytoprotective Effects via ANGPTL4 in a Pre-Clinical Model of Acute Lung Inflammation. [PDF]

FASEB J
Tunstead C, Dunlop M, Ryan S, Volkova E, Johnston E, Batah S, Dos Santos CC, McNicholas B, Masterson C, Laffey JG, English K.   +10 more
europepmc   +1 more source

Stem Cells in Cosmetic Applications: Advancements, Challenges, and Future Directions

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Biotechnology has significantly impacted the cosmetics industry, particularly through the incorporation of plant stem cells, which possess regenerative properties beneficial for skincare. Aims This review aims to evaluate the potential benefits and challenges of using plant stem cells in cosmetics, while discussing future directions
Farid KarkonShayan, Nasim Saderi, Iman Morshedi, Behnaz Ghamari, Sepideh KarkonShayan   +4 more
wiley   +1 more source