Results 201 to 210 of about 61,645 (272)

pH‐Dependent Microenvironmental Ionic Signaling in Pancreatic Ductal Adenocarcinoma

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Pancreatic ductal adenocarcinoma (PDAC) develops within a uniquely dynamic pH landscape shaped by substantial acid–base fluxes produced by the exocrine pancreas. Secretion of alkaline pancreatic juice, normally linked to digestion, produces intermittent acidifications of the pancreatic interstitium, which challenges epithelial and stromal ...
Albrecht Schwab, Micol Rugi, Pawel Swietach, Wiktoria Błaszczak, Ivana Novak, Ganga Deshar, Stine Falsig Pedersen, Renata Ialchina, Albin Sandelin, Jiayi Yao, Stephan J. Reshkin, Rosa A. Cardone, Tiago M. A. Carvalho, Annarosa Arcangeli, Rayhana Bouazzi, Franco N. D'Alessandro, Natalia Prevarskaya, Madelaine M. Audero, Halima Ouadid‐Ahidouch, Julie Schnipper, Luis A. Pardo, Xiaoyi Shi, Frauke Alves, Jakub Mitręga, Anna Trauzold, Sofie E. Hagelund, György Panyi, Marco Cozzolino, Clemens M. W. G. Löwik, Laura Mezzanotte, Roisin McMorrow, Andreas Pahl, Torsten Hechler, Elena Papacharisi, Alessandra Fiorio Pla, Ildiko Szabo, Verena Hofschröer, Zoltán Pethő   +37 more
wiley   +1 more source

Menstrual blood-derived mesenchymal stromal cell secretome modulates macrophage polarization in a preconditioning-dependent manner. [PDF]

Front Cell Dev Biol
de Pedro MÁ, Pulido M, Marchena AM, Álvarez V, González-Nuño FM, Szymański W, Pörschke J, Reinartz S, Graumann J, Pogge von Strandmann E, Sánchez-Margallo FM, Gómez-Serrano M, López E.   +12 more
europepmc   +1 more source

Quiescence of postharvest pathogens: a fungal inhibition process or an immune response of the unripe host fruit?

New Phytologist, Volume 250, Issue 2, Page 812-821, April 2026.
Summary Postharvest pathogens can infect fresh produce both before and after harvest, by direct or wound‐enhanced penetration, remaining quiescent until ripening. Biotrophic‐like postharvest pathogens persist beneath host cells and can remain in a state of quiescence.
Dov B. Prusky, Tong Chen, Yong Chen, Shiping Tian, Boqiang Li   +4 more
wiley   +1 more source

Interleukin 13 (IL-13) Signalling as a Potential Target for Cell Therapies in Liver Fibrosis. [PDF]

Int J Mol Sci
Mazurski A, Bednarz A, Czekaj P.
europepmc   +1 more source

Impact of obesity and an obesogenic environment on cardiotoxin‐induced damage and recovery of human myotubes

Experimental Physiology, Volume 111, Issue 4, Page 2073-2085, 1 April 2026.
Abstract Obesity (BMI ≥ 30 kg/m2) reduces skeletal muscle quality and impairs the myogenic response to muscle damage. The present study investigated if differences exist in myotubes from individuals with (OB) or without (LN) obesity incubated in control (bovine serum albumin [BSA]) or obesogenic (Ob) medium, at baseline or in response to cardiotoxin ...
Brian P. Sullivan, Lundon C. Burton, Allison Ellis, Christopher K. Kargl, Deborah Shera, Shihuan Kuang, James F. Markworth, Timothy P. Gavin   +7 more
wiley   +1 more source

Growth differentiation factor 11 reprograms M2-like macrophages: Targeting immunometabolism for cancer therapy. [PDF]

World J Gastroenterol
Mohammadi S, Darweesh M, Al-Harrasi A.
europepmc   +1 more source

Deciphering Stiffness-Driven Changes in Colorectal Cancer by Proteomics. [PDF]

Mol Cell Proteomics
Cresens C, Montero-Calle A, Solís-Fernández G, Shaghaghi B, Gerrits L, Aytekin S, Kouwer PHJ, Barderas R, Rocha S.   +8 more
europepmc   +1 more source

Does Time Tick Faster in Cerebral Palsy? Accelerated Aging as a Framework for Skeletal Muscle Dysfunction

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Skeletal muscle in individuals with cerebral palsy (CP) may undergo accelerated aging through mechanisms shared with age‐related sarcopenia. Representative overlapping molecular and cellular features include, for example, neuromuscular alterations, impaired satellite cell function and niche composition, chronic inflammation, metabolic deficits, reduced
Oscar Horwath, Sebastian Edman, Sudarshan Dayanidhi, Davis Englund, Mark D. Peterson, Ferdinand von Walden   +5 more
wiley   +1 more source

Mesenchymal Stem Cell Secretome for Cardiac Regeneration: Opportunity for Cell-Free Therapy. [PDF]

Int J Mol Sci
Piotrowska P, Kraskiewicz H, Klimczak A.
europepmc   +1 more source

Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell‐Based Therapies

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Graphical presentation of stem cell‐based therapies for arterial dysfunction, endothelial repair and regeneration strategies. SMC, smooth muscle cell. ABSTRACT Arterial regeneration represents a critical frontier in cardiovascular medicine, as progressive endothelial dysfunction, maladaptive vascular smooth muscle cell (SMC) plasticity, and chronic ...
Yun‐Yu Ma, Shu‐Yao Zhu, Yi Song
wiley   +1 more source