Beyond the Secretory Pathway: New Insights Into Protein Release. [PDF]
In eukaryotes, protein secretion plays essential roles in intercellular communications and extracellular niche-building. Protein secretion generally requires a signal sequence that targets cargos to the canonical secretory pathway consisting of the endoplasmic reticulum (ER), the Golgi apparatus, plasma membrane, and vesicles moving between these ...
Chen RH +34 more
europepmc +2 more sources
Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity [PDF]
Summary: Ionotropic glutamate receptor (iGluR) trafficking and function underpin excitatory synaptic transmission and plasticity and shape neuronal networks.
Ashley J. Evans +4 more
openalex +6 more sources
Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway. [PDF]
Sokoya T +16 more
europepmc +3 more sources
The secretory pathway kinases [PDF]
Protein phosphorylation is a nearly universal post-translation modification involved in a plethora of cellular events. Even though phosphorylation of extracellular proteins had been observed, the identity of the kinases that phosphorylate secreted proteins remained a mystery until only recently.
Anju, Sreelatha +2 more
openaire +2 more sources
The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]
We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Denecke, J. (Jurgen) +6 more
core +2 more sources
A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin +5 more
core +2 more sources
secretion is the movement of material from one point to another .
Ebrahimi, Negar +2 more
openaire +1 more source
Secretory pathways in endothelin synthesis [PDF]
British Journal of Pharmacology (1999) 126, 391–398; doi:10.1038/sj.bjp ...
F D, Russell, A P, Davenport
openaire +2 more sources
Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska +54 more
core +2 more sources
Secretory Pathway of Trypanosomatid Parasites [PDF]
SUMMARYThe Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause important diseases in humans. These include Trypanosoma brucei (the causative agent of African sleeping sickness and nagana in cattle), Trypanosoma cruzi (the causative agent of Chagas' disease in Central and South America), and Leishmania spp.
McConville, Malcolm J. +3 more
openaire +3 more sources

