A secretory kinase complex regulates extracellular protein phosphorylation [PDF]
eLife, 2015 Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Jixin Cui +5 more
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Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity [PDF]
Cell Reports, 2017 Summary: Ionotropic glutamate receptor (iGluR) trafficking and function underpin excitatory synaptic transmission and plasticity and shape neuronal networks.
Ashley J. Evans +4 more
doaj +5 more sources
The Unfolded Protein Response as a Guardian of the Secretory Pathway [PDF]
Cells, 2021 The endoplasmic reticulum (ER) is the major site of membrane biogenesis in most eukaryotic cells. As the entry point to the secretory pathway, it handles more than 10,000 different secretory and membrane proteins.
Toni Radanović, Robert Ernst
doaj +2 more sources
Hijack it, Change it: How do Plant Viruses Utilize the Host Secretory Pathway for Efficient Viral Replication and Spread? [PDF]
Frontiers in Plant Science, 2013 The secretory pathway of eukaryotic cells has an elaborated set of endomembrane compartments involved in the synthesis, modification and sorting of proteins and lipids.
Camilo ePatarroyo +2 more
doaj +3 more sources
Impact of interorganelle coordination between the conventional early secretory pathway and autophagy in cellular homeostasis and stress response [PDF]
Frontiers in Cell and Developmental Biology, 2023 The conventional early secretory pathway and autophagy are two essential interconnected cellular processes that are crucial for maintaining cellular homeostasis.
Diego Tapia +4 more
doaj +2 more sources
Drosophila KDEL receptor function in the embryonic salivary gland and epidermis. [PDF]
PLoS ONE, 2013 Core components of the secretory pathway have largely been identified and studied in single cell systems such as the budding yeast S. cerevisiae or in mammalian tissue culture.
Elliott W Abrams +2 more
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A highly sensitive assay for monitoring the secretory pathway and ER stress. [PDF]
PLoS ONE, 2007 The secretory pathway is a critical index of the capacity of cells to incorporate proteins into cellular membranes and secrete proteins into the extracellular space.
Christian E Badr +3 more
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Cells, 2020 The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic reticulum (ER) to the Golgi are still not well understood.
Sergio Lopez +8 more
doaj +1 more source
Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca2+ in Hansenula polymorpha. [PDF]
PLoS ONE, 2015 Processes taking place in the secretory organelles require Ca2+ and Mn2+, which in yeast are supplied by the Pmr1 ion pump. Here we observed that in the yeast Hansenula polymorpha Ca2+ deficiency in the secretory pathway caused by Pmr1 inactivation is ...
Anastasia V Fokina +4 more
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The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]
, 2003 We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Hadlington, Jane L. +6 more
core +1 more source