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Beyond the Secretory Pathway: New Insights Into Protein Release. [PDF]

open access: yesTraffic
In eukaryotes, protein secretion plays essential roles in intercellular communications and extracellular niche-building. Protein secretion generally requires a signal sequence that targets cargos to the canonical secretory pathway consisting of the endoplasmic reticulum (ER), the Golgi apparatus, plasma membrane, and vesicles moving between these ...
Chen RH   +34 more
europepmc   +2 more sources

Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity [PDF]

open access: gold, 2017
Summary: Ionotropic glutamate receptor (iGluR) trafficking and function underpin excitatory synaptic transmission and plasticity and shape neuronal networks.
Ashley J. Evans   +4 more
openalex   +6 more sources

Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway. [PDF]

open access: goldElife, 2022
Sokoya T   +16 more
europepmc   +3 more sources

The secretory pathway kinases [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2015
Protein phosphorylation is a nearly universal post-translation modification involved in a plethora of cellular events. Even though phosphorylation of extracellular proteins had been observed, the identity of the kinases that phosphorylate secreted proteins remained a mystery until only recently.
Anju, Sreelatha   +2 more
openaire   +2 more sources

The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]

open access: yes, 2003
We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Denecke, J. (Jurgen)   +6 more
core   +2 more sources

A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]

open access: yes, 2015
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin   +5 more
core   +2 more sources

secretory pathway

open access: yes, 2021
secretion is the movement of material from one point to another .
Ebrahimi, Negar   +2 more
openaire   +1 more source

Secretory pathways in endothelin synthesis [PDF]

open access: yesBritish Journal of Pharmacology, 1999
British Journal of Pharmacology (1999) 126, 391–398; doi:10.1038/sj.bjp ...
F D, Russell, A P, Davenport
openaire   +2 more sources

Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]

open access: yes, 2013
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska   +54 more
core   +2 more sources

Secretory Pathway of Trypanosomatid Parasites [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2002
SUMMARYThe Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause important diseases in humans. These include Trypanosoma brucei (the causative agent of African sleeping sickness and nagana in cattle), Trypanosoma cruzi (the causative agent of Chagas' disease in Central and South America), and Leishmania spp.
McConville, Malcolm J.   +3 more
openaire   +3 more sources

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