Results 31 to 40 of about 321,020 (307)
An early secretory pathway mediated by GNOM-LIKE 1 and GNOM is essential for basal polarity establishment in Arabidopsis thaliana [PDF]
, 2015 Spatial regulation of the plant hormone indole-3-acetic acid (IAA, or auxin) is essential for plant development. Auxin gradient establishment is mediated by polarly localized auxin transporters, including PIN-FORMED (PIN) proteins. Their localization and
Doyle, Siamsa M +10 more
core +1 more source
Chloride channels regulate differentiation and barrier functions of the mammalian airway. [PDF]
, 2020 The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction ...
Caplan, Michael J +14 more
core +2 more sources
Recent Developments in Deciphering the Biological Role of Plant Complex N-Glycans
Frontiers in Plant Science, 2022 Asparagine (N)-linked protein glycosylation is a ubiquitous co- and posttranslational modification which has a huge impact on the biogenesis and function of proteins and consequently on the development, growth, and physiology of organisms.
Richard Strasser
doaj +1 more source
Secretory Pathways in Plant Immune Responses [PDF]
Plant Physiology, 2008 Innate immune receptors in plants detect the presence of microbial pathogens and trigger defense responses to terminate or restrict pathogen growth. The molecular mechanisms of receptor-mediated nonself recognition and subsequent intracellular signaling pathways have received much attention in ...
Kwon, C. +2 more
openaire +3 more sources
Microbial Cell Factories, 2023 Trichoderma reesei (T. reesei) is well-known for its excellent ability to secret a large quantity of cellulase. However, unlike the endogenous proteins, little is known about the molecular mechanisms governing heterologous protein production.
Wangli Ji +10 more
doaj +1 more source
Journal of Pharmacological Sciences, 2004 To examine the unknown trafficking pathway of the cystic fibrosis transmembrane conductance regulator (CFTR) from the endoplasmic reticulum (ER), we utilized baby hamster kidney cells stably expressing CFTR fused with green fluorescent protein.
Tsukasa Okiyoneda +8 more
doaj +1 more source
An amphipathic alpha-helix in the prodomain of cocaine and amphetamine regulated transcript peptide precursor serves as its sorting signal to the regulated secretory pathway. [PDF]
PLoS ONE, 2013 Cocaine and Amphetamine Regulated Transcript (CART) peptides are anorexigenic neuropeptides. The L34F mutation in human CART peptide precursor (proCART) has been linked to obesity (Yanik et al. Endocrinology 147: 39, 2006).
Elías H Blanco +3 more
doaj +1 more source
Plant Protein O-Arabinosylation
Frontiers in Plant Science, 2021 A wide range of proteins with diverse functions in development, defense, and stress responses are O-arabinosylated at hydroxyprolines (Hyps) within distinct amino acid motifs of continuous stretches of Hyps, as found in the structural cell wall extensins,
Bent Larsen Petersen +2 more
doaj +1 more source
HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification [PDF]
, 2017 Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are ...
Asensio, Cedric S +7 more
core +2 more sources
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway
Nature Communications, 2019 Zinc ions (Zn2+) are imported by Golgi-resident transporters but the function of zinc in the early secretory pathway has remained unknown. Here the authors find that Zn2+ regulates protein quality control in the early secretory pathway by demonstrating ...
Satoshi Watanabe +10 more
doaj +1 more source