Results 91 to 100 of about 2,027 (239)
New Discoveries with Mice Mutant in Endothelial and Platelet Selectins
, 1999 IntroductionThe selectin family of adhesion receptors consists of three members: P-, E-, and L-selectin. P-selectin is constitutively present in the α-granules of platelets and Weibel-Palade bodies of endothelial cells and is rapidly translocated to the ...
Denisa Wagner, Daqing Hartwell
core +1 more source
BMEMat, EarlyView.Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang +8 more
wiley +1 more source
BMEMat, EarlyView.A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue +4 more
wiley +1 more source
Circulating cell adhesion molecules in systemic sclerosis: a systematic review and meta-analysis
Frontiers in ImmunologyIntroductionPatients with systemic sclerosis (SSc) have an increased risk of endothelial dysfunction, atherosclerosis, and cardiovascular events compared to the general population.
Arduino A. Mangoni +2 more
doaj +1 more source
Soluble Selectin Levels in Patients with Lung Cancer
The International Journal of Biological Markers, 2002 Increased expression of selectins has been found on endothelial cells of venules and capillaries in the tumor stroma of non-small cell lung cancer, suggesting their functional role in the process of chemotaxis for tumor cells. The present study was aimed
M. Roselli +9 more
doaj +1 more source
Endothelial expression of selectins during endotoxin preconditioning
, 2000 Although bacterial endotoxins [lipopolysaccharide (LPS)] can confer tissue resistance to subsequent inflammatory insults, the mechanisms that underlie this LPS-preconditioning (LPS-PC) response remain poorly defined.
D. Neil Granger +4 more
core +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Frontiers in ImmunologyBackgroundEarly diagnosis and treatment of Systemic lupus erythematosus (SLE) and Systemic sclerosis (SSc) present significant challenges for clinicians.
Esther San Antonio +19 more
doaj +1 more source
P‐selectin in haemostasis [PDF]
British Journal of Haematology, 2004 SummaryDuring the past decade, interrelationships between inflammation and thrombosis have been the subject of extensive works, and it is now commonly recognized that inflammation (notably leucocyte recruitment) directly affects thrombosis, and that thrombosis also constitutes a pro‐inflammatory event.
openaire +2 more sources
Selectins mediate macrophage infiltration in obstructive nephropathy in newborn mice11See Editorial by Kipari and Hughes, p. 760. [PDF]
, 2002 Selectins mediate macrophage infiltration in obstructive nephropathy in newborn mice.BackgroundUrinary tract obstruction during development leads to tubular atrophy and causes interstitial fibrosis.
Cachat, Francois +3 more
core +1 more source