Results 71 to 80 of about 14,056 (288)
P-Selectin, and Not E-Selectin, Negatively Regulates Murine Megakaryocytopoiesis [PDF]
The Journal of Immunology, 2002 Abstract To assess the role of P-selectin and E-selectin in megakaryocytopoiesis, in vitro assays were performed in animal models deficient in both adhesion receptors. There was a significantly greater number of IL-3-responsive megakaryocyte progenitors CFU (CFU-MK) and an increase in immature megakaryoblasts in response to IL-6 in ...
Naheed, Banu +2 more
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Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li +6 more
wiley +1 more source
Modulation of Animal Gut Health by Milk Oligosaccharide
Animal Research and One Health, EarlyView.This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen +7 more
wiley +1 more source
Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotype
Journal of Inflammation, 2011 Objective The recruitment of leukocytes from circulation to sites of inflammation requires several families of adhesion molecules among which are selectins expressed on a variety of cells.
Banerjee Ena
doaj +1 more source
New Discoveries with Mice Mutant in Endothelial and Platelet Selectins
, 1999 IntroductionThe selectin family of adhesion receptors consists of three members: P-, E-, and L-selectin. P-selectin is constitutively present in the α-granules of platelets and Weibel-Palade bodies of endothelial cells and is rapidly translocated to the ...
Denisa Wagner, Daqing Hartwell
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
CHIMIA, 2007 Selectins play a key role in leukocyte trafficking during the inflammatory response of the organism, i.e. the recruitment and extravasation of leukocytes from the blood stream into inflamed tissue.
Alexander Titz, Beat Ernst
doaj +1 more source
Cadherins, Selectins, and Integrins in CAM-DR in Leukemia
Frontiers in Oncology, 2020 The interaction between leukemia cells and the bone microenvironment is known to provide drug resistance in leukemia cells. This phenomenon, called cell adhesion-mediated drug resistance (CAM-DR), has been demonstrated in many subsets of leukemia ...
Hye Na Kim +4 more
doaj +1 more source
The Journal of Immunology, 2006 By 1983, when the article by Gallatin, Weissman, and Butcher ([1][1]) was published in Nature , it was clear that blood-borne lymphocytes migrate selectively (“home”) to secondary lymphoid organs.
openaire +2 more sources