Results 191 to 200 of about 14,056 (288)

Landscape of Immune Remodeling and NAP1L1‐Driven Epithelial Reprogramming in Gastric Cancer Metastasis

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 126-138, June 2026.
High‐resolution single‐cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in each lesion. (C) Cells annotation by canon markers for all cells. (D) Bubble chart for canon marker genes for each cell subtype.
Min Sun, Yuanzhi Wang, Yuqing Zhang, Xiaojuan Wang   +3 more
wiley   +1 more source

Biophysical adaptations of circulating tumor cells undergoing metastasis. [PDF]

Biophys Rep
Liang L, Song X, Wang S, Lim CT.
europepmc   +1 more source

Effects of Chemotherapeutic Agents (5-Fluorouracil, Cisplatin and Methotrexate) on Cell Adhesion Molecules and Oxidative Damage Markers in Rat Kidney Tissue. [PDF]

Basic Clin Pharmacol Toxicol
Chemotherapy with 5‐fluorouracil, cisplatin or methotrexate induces significant renal oxidative stress, DNA damage and dysregulation of apoptosis‐ and cell adhesion‐related proteins in rats. Cisplatin causes the most severe oxidative injury, whereas methotrexate predominantly alters apoptotic and cell adhesion pathways.
Ozyapici SE, Dundar MO, Atakisi O.
europepmc   +2 more sources

Adjunctive Methylprednisolone After Thrombectomy: A Secondary Analysis Stratified by Admission White Blood Cell Count

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Admission WBC identified who benefited from adjunctive methylprednisolone after thrombectomy. Improved 90‐day function and lower mortality/pneumonia occurred only with WBC ≥ 10 × 109/L, supporting WBC‐guided corticosteroid targeting. ABSTRACT Background Leukocyte‐driven inflammation may contribute to reperfusion–outcome mismatch after thrombectomy.
Chengsong Yue, Jie Yang, Dahong Yang, Guanting Heng, Linyu Li, Shihai Yang, Xuanyu Chen, Yi Lin, Kunxin Lin, Wenjie Zi   +9 more
wiley   +1 more source

The Role of Glycans in Human Immunity-A Sweet Code. [PDF]

Molecules
Tvaroška I.
europepmc   +1 more source

Orexin B Reduces Cerebral Aneurysms Through Inhibition of SP‐1

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Orexin B/OX2R signaling attenuates cerebral aneurysm formation by suppressing SP‐1‐mediated inflammation, macrophage infiltration, and endothelial adhesion, with OX2R knockdown abolishing these protective effects. The study highlights Orexin B as a therapeutic candidate targeting vascular inflammation and remodeling in aneurysms.
Lei Chen, Jinlong Xu, Fengyun Ye, Jiajia Luo, Huimin Yu   +4 more
wiley   +1 more source

Extracellular Vesicles as Drivers of Lung Endothelial Dysfunction in ARDS: Mechanisms and Therapeutic Opportunities

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni, Patrick Belvitch, Steven M. Dudek, Eleftheria Letsiou   +3 more
wiley   +1 more source

Key role of the endothelium in lung ischemia-reperfusion injury: What the clinician needs to know. [PDF]

JHLT Open
Besnier E, Clavier T, Bellien J, Selim J.   +3 more
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Severe Eosinophilic Asthma: From Immunopathology to Pharmacological Treatment. [PDF]

J Clin Med
Pastore D, Lupia C, Chiarella E, Piazzetta GL, Mazza G, Neri G, Petrone A, Bruni A, Longhini F, Garofalo E, Pelaia G, Pelaia C.   +11 more
europepmc   +1 more source