Results 11 to 20 of about 298,238 (306)
Research on selective uptake of photosensitizer C3N4@RP by different cancer cells
Materials Research Express, 2022 Photodynamic therapy (PDT), as a clinical treatment, can remove malignant cells upon laser irradiation by selective uptake of photosensitizer (PS). The relative contribution of these antitumor effects depends largely on the dose and uptake of PS. In this
Jiaxiu Liu +3 more
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LDL and HDL enriched in triglyceride promote abnormal cholesterol transport
Journal of Lipid Research, 2002 Hypertriglyceridemia induces multiple changes in lipoprotein composition. Here we investigate how one of these modifications, triglyceride (TG) enrichment, affects HDL and LDL function when this alteration occurs under conditions in which more polar ...
Josephine W. Skeggs, Richard E. Morton
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Selective uptake of cadmium by the parenchyumal cells of liver [PDF]
Biochemical Journal, 1980 The uptake of cadmium in vivo into parenchymal and non-parenchymal (sinusoidal) cells of the liver was studied by a cell-separation technique. Liver parenchymal cells accumulate cadmium more readily than do non-parenchymal cells and synthesize metallothionein.
K, Cain, D N, Skilleter
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Scavenger receptor class B type I localizes to a late endosomal compartment
Journal of Lipid Research, 2008 Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues.
Malika Ahras, Thet Naing, Ruth McPherson
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Zinc oxide nanoparticles as selective killers of proliferating cells [PDF]
, 2011 Background: It has recently been demonstrated that zinc oxide nanoparticles (ZnO NPs) induce death of cancerous cells whilst having no cytotoxic effect on normal cells.
Liuba Taccola +28 more
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Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function
Journal of Lipid Research, 2007 Scavenger receptor class B type I (SR-BI) facilitates the uptake of HDL cholesteryl esters (CEs) in a two-step process involving binding of HDL to its extracellular domain and transfer of HDL core CEs to a metabolically active membrane pool, where they ...
Saj Parathath +7 more
doaj +1 more source
New developments in selective cholesteryl ester uptake [PDF]
Current Opinion in Lipidology, 2013 Selective lipid uptake (SLU) is known to be a major pathway of lipoprotein cholesterol metabolism in experimental animals and humans, but remains poorly understood. This review provides a brief overview of SLU mediated by the HDL receptor scavenger receptor B-type I (SR-BI), and highlights several surprising new findings related to the impact of SLU ...
Jason M, Meyer +2 more
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Journal of Lipid Research, 2008 Neutral cholesteryl ester hydrolase (CEH)-mediated hydrolysis of cellular cholesteryl esters (CEs) is required not only to generate free cholesterol (FC) for efflux from macrophages but also to release FC from lipoprotein-delivered CE in the liver for ...
Bin Zhao, Jingmei Song, Shobha Ghosh
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Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Transporter [PDF]
, 2010 <b>Background</b>: Plasmodium parasites are unable to synthesize purines de novo and have to salvage them from the host. Due to this limitation in the parasite, purine transporters have been an area of focus in the search for anti-malarial ...
Neils B Quashie +8 more
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SR-BI-directed HDL-cholesteryl ester hydrolysis
Journal of Lipid Research, 2003 We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid and ...
Margery A. Connelly +3 more
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