Results 81 to 90 of about 298,238 (306)

Selective Serotonin Re-uptake Inhibitors: An Overview

Psychiatry and Clinical Psychopharmacology, 2021
Over the past decade there has been a crescendo of interest in the role of the serotonin system in mediating both anxiety and depressive disorders. Researchs has provided therapeutic compounds that are selective for re-uptake blockade in the serotonin ...
İsmail ÇİFTER
doaj  

Expression and microvillar localization of scavenger receptor class B, type I (SR-BI) and selective cholesteryl ester uptake in Leydig cells from rat testis

Journal of Lipid Research, 2000
: This study investigates the relationship between the high density lipoprotein (HDL) receptor (scavenger receptors, SR-BI and SR-BII), selective lipoprotein-cholesteryl ester uptake, and testosterone production in Leydig cells of control ...
Eve Reaven, Lichun Zhan, Ann Nomoto, Susan Leers-Sucheta, Salman Azhar   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Growing gold nanostructures for shape-selective cellular uptake

Nanoscale Research Letters, 2018
With development in the synthesis of shape- and size-dependent gold (Au) nanostructures (NSs) and their applications in nanomedicine, one of the biggest challenges is to understand the interaction of these shapes with cancer cells.
Sulalit Bandyopadhyay, Birgitte H. McDonagh, Gurvinder Singh, Karthik Raghunathan, Axel Sandvig, Ioanna Sandvig, Jens-Petter Andreassen, Wilhelm R. Glomm   +7 more
doaj   +1 more source

High and selective CO2 uptake, H2 storage and methanol sensing on the amine-decorated 12-connected MOF CAU-1

, 2011
High and selective CO2 uptake, H2 storage and methanol sensing on the amine-decorated 12-connected MOF CAU-
徐芬, 张箭, 李芬, 司晓亮, 孙立贤, 焦成丽, 李志宝, ZelimirGabelica, 王爽, ChristophSchick, 刘双   +10 more
core  

Chronic cocaine increases κ‐opioid receptor density: Lack of effect by selective dopamine uptake inhibitors

, 2002
Continuous infusion of cocaine or the selective dopamine uptake inhibitors GBR 12909 or RTI‐117 increases locomotor stimulation, to which partial tolerance occurs.
Kunko, Paul M, Collins, Stephanie L, Ladenheim, Bruce, Cadet, Jean‐Lud, Carroll, F. Ivy, Izenwasser, Sari   +5 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Bile acids reduce endocytosis of high-density lipoprotein (HDL) in HepG2 cells.

PLoS ONE, 2014
High-density lipoprotein (HDL) transports lipids to hepatic cells and the majority of HDL-associated cholesterol is destined for biliary excretion. Cholesterol is excreted into the bile directly or after conversion to bile acids, which are also present ...
Clemens Röhrl, Karin Eigner, Stefanie Fruhwürth, Herbert Stangl   +3 more
doaj   +1 more source

Characteristics of cadmium uptake in two contrasting ecotypes of the hyperaccumulator Thlaspi caerulescens

, 2002
Copyright © 2002 Oxford University PressUptake of Cd and Zn by intact seedlings of two contrasting ecotypes of the hyperaccumulator Thlaspi caerulescens was characterized using radioactive tracers.
Zhao, F., McLaughlin, M., Hamon, R. E., Mclaughlin, M. J., Zhao, F-J., Hamon, R., McGrath, S. P., McGrath, S., Lombi, E.   +8 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source