Results 61 to 70 of about 298,238 (306)

Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) has been identified as a functional HDL binding protein that can mediate the selective uptake of cholesteryl ester (CE) from HDL.
Ruud Out, Menno Hoekstra, John A.A. Spijkers, Johan K. Kruijt, Miranda van Eck, Ingrid S.T. Bos, Jaap Twisk, Theo J.C. Van Berkel   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Regulation of the selective uptake of high density lipoprotein-associated cholesteryl esters by human fibroblasts and Hep G2 hepatoma cells.

Journal of Lipid Research, 1988
We have previously shown that the liver and steroidogenic tissues of rats in vivo and a wider range of cells in vitro, including human cells, selectively take up high density lipoprotein (HDL) cholesteryl esters without parallel uptake of HDL particles ...
F Rinninger, R C Pittman
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Simultaneous induction of an HDL receptor protein (SR-BI) and the selective uptake of HDL-cholesteryl esters in a physiologically relevant steroidogenic cell model

Journal of Lipid Research, 1998
This study addresses the question of whether the level of expression of SR-BI (an HDL receptor) is linked to the expression of selective lipoprotein-cholesteryl ester delivery in a steroidogenic cell model. Rat ovarian granulosa cells are physiologically
Salman Azhar, Ann Nomoto, Susan Leers-Sucheta, Eve Reaven   +3 more
doaj   +1 more source

Zebrafish kidney phagocytes utilize macropinocytosis and Ca+-dependent endocytic mechanisms. [PDF]

PLoS ONE, 2009
BACKGROUND: The innate immune response constitutes the first line of defense against invading pathogens and consists of a variety of immune defense mechanisms including active endocytosis by macrophages and granulocytes.
Claudia Hohn, Sang-Ryul Lee, Lesya M Pinchuk, Lora Petrie-Hanson   +3 more
doaj   +1 more source

Selective uptake of cholesteryl ester in plasma and liver.

, 2013
[A] Uptake of [125I] upper panel and [3H] lower panel in plasma over 24 hrs and in tissues: liver, adrenals, testis and kidney at 24 hrs.
Yanina Langle (360584), John S. Millar (371292), Sara K. VanOrman (371290), Ioannis M. Stylianou (371288), Daniel J. Rader (113673), Karen L. Svenson (310958), Beverly Paigen (18314)   +6 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Thematic Review Series: Lipid Transfer Proteins Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

Journal of Lipid Research, 2018
Cholesterol is required for maintenance of plasma membrane fluidity and integrity and for many cellular functions. Cellular cholesterol can be obtained from lipoproteins in a selective pathway of HDL-cholesteryl ester (CE) uptake without parallel ...
Wen-Jun Shen, Shailendra Asthana, Fredric B. Kraemer, Salman Azhar   +3 more
doaj   +1 more source

Selective gonadotrophin uptake by mouse ovarian carcinoma [PDF]

Experientia, 1972
Bei Mausen mit Granulosa- oder Theca-Tumoren wurde die Bindung von125I-HCG untersucht. Im Vergleich zur Bindung an andere Gewebe derselben Tiere konnte eine zellspezifische Bindung im Bereich der Tumoren festgestellt werden. Die Befunde werden im Zusammenhang mit der Zweizelltheorie der ovariellen Steroidgenese diskutiert.
openaire   +3 more sources