Results 51 to 60 of about 1,856,845 (304)

Regulation of the selective uptake of cholesteryl esters from high density lipoproteins by sphingomyelin

open access: yesJournal of Lipid Research, 2005
Although sphingomyelin (SM) is a major phospholipid in lipoproteins as well as in the membrane rafts where the scavenger receptor class B type I (SR-BI) is localized, its possible role in the selective uptake of cholesteryl ester (CE) by the SR-BI ...
Papasani V. Subbaiah   +2 more
doaj   +1 more source

Quantitative assessment of the comparative nanoparticle-uptake efficiency of a range of cell lines [PDF]

open access: yes, 2011
Interest continues to grow in the possibility of understanding the mechanism(s) of nanoparticle-cell interactions. At present there is little knowledge, and essentially no understanding, of the relevant length and time scales for nanoparticle ...
Dawson, Kenneth A   +15 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor B1

open access: yesJournal of Lipid Research, 1999
Hepatic lipase (HL) plays a major role in high-density lipoprotein (HDL) metabolism both as a lipolytic enzyme and as a ligand. To investigate whether HL enhances the uptake of HDL-cholesteryl ester (CE) via the newly described scavenger receptor BI (SR ...
Gilles Lambert   +5 more
doaj   +1 more source

Research on selective uptake of photosensitizer C3N4@RP by different cancer cells

open access: yesMaterials Research Express, 2022
Photodynamic therapy (PDT), as a clinical treatment, can remove malignant cells upon laser irradiation by selective uptake of photosensitizer (PS). The relative contribution of these antitumor effects depends largely on the dose and uptake of PS. In this
Jiaxiu Liu   +3 more
doaj   +1 more source

Identification and functional characterisation of a class on non-selective cation channels in Saccharomyces cerevisiae. [PDF]

open access: yes, 2009
Na⁺ accumulation is a significant component in salt toxicity in plants. Although many proteins that facilitate Na⁺ flux have been identified in plants, investigations aimed at identifying the initial mechanism of Na⁺ entry into plants have failed.
Carter, Scott Anthony William
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice

open access: yesJournal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) has been identified as a functional HDL binding protein that can mediate the selective uptake of cholesteryl ester (CE) from HDL.
Ruud Out   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Regulation of the selective uptake of high density lipoprotein-associated cholesteryl esters by human fibroblasts and Hep G2 hepatoma cells.

open access: yesJournal of Lipid Research, 1988
We have previously shown that the liver and steroidogenic tissues of rats in vivo and a wider range of cells in vitro, including human cells, selectively take up high density lipoprotein (HDL) cholesteryl esters without parallel uptake of HDL particles ...
F Rinninger, R C Pittman
doaj   +1 more source

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