Mercury and selenium binding biomolecules in terrestrial mammals (Cervus elaphus and Sus scrofa) from a mercury exposed area [PDF]
, 2017 Acknowledgements The authors are grateful to Junta de Comunidades de Castilla-La Mancha (PCC-05-004-2, PAI06-0094, PCI-08-0096, PEII09-0032-5329) and the Ministerio de Economía y Competitividad (CTQ2013-48411-P) for financial support. M.J.
Fariñas, N. Rodríguez +5 more
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Advanced Biomedical Research, 2019 Background: Colorectal cancer (CRC) is rated as the second cause of cancer death worldwide. Selenium (Se) has antioxidant activity and antitumor effect, especially in colon cancer. This important role occurs through selenoproteins.
Guilda Amini +5 more
doaj +1 more source
Solution Structures of \u3cem\u3eMycobacterium tuberculosis\u3c/em\u3e Thioredoxin C and Models of Intact Thioredoxin System Suggest New Approaches to Inhibitor and Drug Design [PDF]
, 2013 Here, we report the NMR solution structures of Mycobacterium tuberculosis (M. tuberculosis) thioredoxin C in both oxidized and reduced states, with discussion of structural changes that occur in going between redox states.
Cai, Sheng +3 more
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On the road to selenocysteine [PDF]
Proceedings of the National Academy of Sciences, 2004 Decades ago, a mammalian tRNA that exclusively bound the UGA stop codon was identified by using the triplet binding assay that was instrumental in deciphering the genetic code (1). The possibility of a naturally occurring suppressor tRNA presented the dilemma of explaining the biological function of such a molecule.
openaire +2 more sources
Complete Genome Sequence of the Citrobacter freundii Type Strain. [PDF]
, 2020 Citrobacter freundii is a species of facultative anaerobic Gram-negative bacteria of the family Enterobacteriaceae The complete genome is composed of a single chromosomal circle of 4,957,773 bp with a G+C content of 52%
Booth, Benjamin W +5 more
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Defining the methanogenic SECIS element in vivo by targeted mutagenesis
RNA BiologyIn all domains of life, Archaea, Eukarya and Bacteria, the unusual amino acid selenocysteine (Sec) is co-translationally incorporated into proteins by recoding a UGA stop codon to a sense codon.
Nils Peiter +5 more
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The role of selenium in nutrition – A review
Acta Universitatis Sapientiae: Alimentaria, 2018 The role of selenium has been changed over the last decade. The element that was previously considered to be toxic turned out to be present in the human body in amounts of 10–15 mg, and almost every cell of our body contains it.
Tóth R. Juhászné, Csapó J.
doaj +1 more source
Selenoproteins in mammalian spermatogenesis:role of the nuclear GPx4 [PDF]
, 2011 The selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx/GPx4) is an enzyme unique among the various GPxs, because it is able to use protein thiols, beside glutathione, The GPx4 gene encodes for three isoforms having different ...
Maccari, Irene
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Characterization of Fungal Communities Associated with Aquilaria spp. for the Production of Agarwood. [Poster-B123] [PDF]
, 2018 Aquilaria is a tree genus distributed in Southeast Asia, known for its oleoresin production. The induction of this oleoresin is described as a stress reaction by injury and, or fungal infection. In response to this stress, Aquilaria spp.
Amusant, Nadine +7 more
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Why do proteins use selenocysteine instead of cysteine? [PDF]
, 2018 Selenocysteine is present in a variety of proteins and catalyzes the oxidation of thiols to disulfides and the reduction of disulfides to thiols. Here, we compare the kinetic and thermodynamic properties of cysteine with its selenium-containing analogon,
Koppenol, Willem +2 more
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