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Selenium and Selenocysteine in Protein Chemistry

Angewandte Chemie - International Edition, 2017
AbstractSelenocysteine, the selenium‐containing analogue of cysteine, is the twenty‐first proteinogenic amino acid. Since its discovery almost fifty years ago, it has been exploited in unnatural systems even more often than in natural systems. Selenocysteine chemistry has attracted the attention of many chemists in the field of chemical biology owing ...
Norman Metanis
exaly   +3 more sources

Selenocysteine

Annual Review of Biochemistry, 1996
Selenocysteine is recognized as the 21st amino acid in ribosome-mediated protein synthesis and its specific incorporation is directed by the UGA codon. Unique tRNAs that have complementary UCA anticodons are aminoacylated with serine, the seryl-tRNA is converted to selenocysteyl-tRNA and the latter binds specifically to a special elongation factor and
K, Forchhammer, K, Boesmiller, A, Böck
openaire   +4 more sources

Selenocysteine

EcoSal Plus, 2004
About 50 years ago, research on the biological function of the element selenium was initiated by the report of J. Pinsent that generation of formate dehydrogenase activity by Escherichia coli requires the presence of both selenite and molybdate in the growth medium.
Böck, A.   +1 more
openaire   +3 more sources

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