Thioredoxin reductase as a target enzyme for electrophilic anticancer drugs [PDF]
, 2011 Induced production of reactive oxygen species (ROS) is a common attribute of most cancer cells. One strategy for cancer cells to maneuver the increased and potentially toxic levels of ROS is to induce the expression of cellular antioxidants and ...
Eriksson, Sofi
core +1 more source
Selenoprotein P inhibits cell proliferation and ROX production in HCC cells.
PLoS ONE, 2020 Selenoprotein P (SEPP1) is a kind of secretory glycoproteins with an antioxidant effect during the development of some diseases. In this study, we attempted to observe the expression of SEPP1 in livers from the patients with hepatocellular carcinoma (HCC)
Jianxin Wang +8 more
doaj +1 more source
Pro198Leu polymorphism affects the selenium status and GPx activity in response to Brazil nut intake [PDF]
, 2016 © The Royal Society of Chemistry 2015. Selenoproteins play important roles in antioxidant mechanisms, and are thus hypothesised to have some involvement in the pathology of certain types of dementia.
Busse, AL +8 more
core +1 more source
Corrigendum: Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans [PDF]
, 2021 Yuki Isobe +13 more
openalex +1 more source
Ccdc152 is not necessary for male fertility, but contributes to maintaining sperm morphology
The Journal of Reproduction and DevelopmentSelenoprotein P (SeP) is synthesized in the liver and plays a vital role in maintaining selenium homeostasis via transport throughout the body. Previous studies have shown that SeP-deficient mice have severely reduced expression of selenoproteins ...
Ryua HARIMA +8 more
doaj +1 more source
BMC Medical Genetics, 2017 Background Selenium is an essential trace and there is a high selenium concentration in the thyroid gland. Selenium deficiency may impair the thyroid function.
Ling Xiao +8 more
doaj +1 more source
Determinants of selenium status in healthy adults
Nutrition Journal, 2011 Background Selenium (Se) status in non-deficient subjects is typically assessed by the Se contents of plasma/serum. That pool comprises two functional, specific selenoprotein components and at least one non-functional, non-specific components which ...
Hoeg Antonia +11 more
doaj +1 more source
Regulation of selenoprotein P concentration and expression by different sources of selenium in broiler breeders and their offspring [PDF]
, 2013 Dong Yuan +4 more
openalex +1 more source
Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation [PDF]
, 2021 Yuichiro Mita +12 more
openalex +1 more source
Levels of circulating selenoprotein P, fibroblast growth factor (FGF) 21 and FGF23 in relation to the metabolic syndrome in young children [PDF]
, 2014 Ko Bj +4 more
openalex +1 more source