The genomes of two key bumblebee species with primitive eusocial organization [PDF]
, 2015 Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies.
Amdam, Gro V. +143 more
core +17 more sources
Selenium supplementation of lactating dairy cows: effects on milk production and total selenium content and speciation in blood, milk and cheese [PDF]
, 2008 Forty-multiparous Holstein cows were used in a 16-wk continuous design study to determine the effects of either selenium (Se) source, selenized yeast (SY) (derived from a specific strain of Saccharomyces cerevisiae CNCM I-3060 Sel-Plex®) or sodium ...
Bertin, Gérard +5 more
core +1 more source
Selenoprotein-Transgenic Chlamydomonas reinhardtii [PDF]
Nutrients, 2013 Selenium (Se) deficiency is associated with the occurrence of many diseases. However, excessive Se supplementation, especially with inorganic Se, can result in toxicity. Selenoproteins are the major forms of Se in vivo to exert its biological function. Expression of those selenoproteins, especially with the application of a newly developed system,
Hou, Qintang +5 more
openaire +2 more sources
Glutathione-Mediated Neuroprotection Against Methylmercury Neurotoxicity in Cortical Culture is Dependent on MRP1 [PDF]
, 2012 Methylmercury (MeHg) exposure at high concentrations poses significant neurotoxic threat to humans worldwide. The present study investigated the mechanisms of glutathione-mediated attenuation of MeHg neurotoxicity in primary cortical culture. MeHg (5 μM)
Liu, Xiaoqian +4 more
core +1 more source
Thioredoxin reductase as a target enzyme for electrophilic anticancer drugs [PDF]
, 2011 Induced production of reactive oxygen species (ROS) is a common attribute of most cancer cells. One strategy for cancer cells to maneuver the increased and potentially toxic levels of ROS is to induce the expression of cellular antioxidants and ...
Eriksson, Sofi
core +1 more source
Exploring the importance of sulfate transporters and ATP sulphurylases for selenium hyperaccumulation\u2014a comparison of Stanleya pinnata and Brassica juncea (Brassicaceae) [PDF]
, 2015 Selenium (Se) hyperaccumulation, the capacity of some species to concentrate Se to levels upwards of 0.1% of dry weight, is an intriguing phenomenon that is only partially understood.
Elizabeth A. H., Pilon Smits +3 more
core +1 more source
SECISearch3 and Seblastian: new tools for prediction of SECIS elements and selenoproteins [PDF]
, 2014 Selenoproteins are proteins containing an uncommon amino acid selenocysteine (Sec). Sec is inserted by a specific translational machinery that recognizes a stem-loop structure, the SECIS element, at the 3′ UTR of selenoprotein genes and recodes a UGA ...
Gladyshev, Vadim N. +3 more
core +1 more source
Eukaryotic selenoproteins and selenoproteomes
Biochimica et Biophysica Acta (BBA) - General Subjects, 2009 Selenium is an essential trace element for which both beneficial and toxic effects in human health have been described. It is now clear that the importance of having adequate amounts of this micronutrient in the diet is primarily due to the fact that selenium is required for biosynthesis of selenocysteine, the twenty first naturally occurring amino ...
Lobanov, Alexey V. +2 more
openaire +3 more sources
Glutathione Enzyme and Selenoprotein Polymorphisms Associate with Mercury Biomarker Levels in Michigan Dental Professionals [PDF]
, 2011 Mercury is a potent toxicant of concern to both the general public and occupationally exposed workers (e.g., dentists). Recent studies suggest that several genes mediating the toxicokinetics of mercury are polymorphic in humans and may influence inter ...
Basu, Niladri +5 more
core +1 more source
Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P [PDF]
, 2017 Selenoprotein P (SELENOP) is a liver-derived transporter of selenium (Se) in blood, and a meaningful biomarker of Se status. Se is an essential trace element for the biosynthesis of enzymatically-active selenoproteins, protecting the organism from ...
Hybsier, Sandra +10 more
core +1 more source