Results 41 to 50 of about 7,542 (180)

Emerging roles of selenium on metabolism and type 2 diabetes

Frontiers in Nutrition, 2022
Selenium is recognized as an essential element for human health and enters human body mainly via diet. Selenium is a key constituent in selenoproteins, which exert essential biological functions, including antioxidant and anti-inflammatory effects ...
Jiuxiang Zhao, Hong Zou, Yanling Huo, Xiaoyi Wei, Yu Li   +4 more
doaj   +1 more source

Bifunctional injectable selenium‐containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation

BMEMat, EarlyView.
Graphical illustration of the synthesis, biological functions and mechanisms of bifunctional injectable selenium‐containing polyurethane hydrogels. Abstract Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment.
Mingchu Zhao, Mo Zhai, Zhuoxin Ge, Xiaodong Guo, Zhuqing Wan, Xiaoqiang Bai, Huaping Xu, Yongsheng Zhou, Longwei Lv   +8 more
wiley   +1 more source

Prospects for the use of synthetic organoselenium compounds for the correction of metabolic and immune status during vaccination with live attenuated vaccines against especially dangerous infections

Acta Biomedica Scientifica, 2021
This review article analyzes the data on the role of selenium in the regulation of the metabolic and immune status of a macroorganism. The data on endogenousfunctional selenium-containing molecules, which include selenocysteine, selenomethionine, and ...
O. V. Yurieva, V. I. Dubrovina, A. B. Pyatidesyatnikova   +2 more
doaj   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

Biological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Eukaryotic selenoproteins and selenoproteomes

Biochimica et Biophysica Acta (BBA) - General Subjects, 2009
Selenium is an essential trace element for which both beneficial and toxic effects in human health have been described. It is now clear that the importance of having adequate amounts of this micronutrient in the diet is primarily due to the fact that selenium is required for biosynthesis of selenocysteine, the twenty first naturally occurring amino ...
Lobanov, Alexey V., Hatfield, Dolph L., Gladyshev, Vadim N.   +2 more
openaire   +3 more sources

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a serious illness in which more than half of all deaths are due to malnutrition. Critically low energy and protein intake are known causes of massive weight loss, whereas micronutrient deficiencies due to a low‐calorie food pattern remain poorly characterized in children with AN. Micronutrient deficiencies in
Zenaida Iordan, Diane Morfin, Marion Bernetiere, Marie Fauchet, Noël Peretti, Bérénice Segrestin, Pierre Poinsot   +6 more
wiley   +1 more source

Mechanism of Selenoprotein Expression and Enzymatic Activity Characteristics in Natural Lactococcus lactis [PDF]

Shipin Kexue
We aimed to investigate the expression of selenocysteine (Sec)-containing selenoproteins in natural Lactococcus lactis and to analyze the differences in glutathione peroxidase (GPx) activity among the recombinant L.
PENG Jingjing, YUE Shiyang, LU Lianghua, LIU Xiaoling, WANG Chenghua
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Dual incorporation of non-canonical amino acids enables production of post-translationally modified selenoproteins

Frontiers in Molecular Biosciences, 2023
Post-translational modifications (PTMs) can occur on almost all amino acids in eukaryotes as a key mechanism for regulating protein function. The ability to study the role of these modifications in various biological processes requires techniques to ...
Pearl Morosky, Cody Comyns, Lance G. A. Nunes, Christina Z. Chung, Peter R. Hoffmann, Dieter Söll, Dieter Söll, Oscar Vargas-Rodriguez, Natalie Krahn   +8 more
doaj   +1 more source

A Crystalline and Thermally Stable Selenocysteine Selenenic Acid

Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.
The long‐sought catalytic intermediate of selenoproteins, selenocysteine selenenic acid (Sec–SeOH), is isolated for the first time at ambient temperature. A bioinspired selenopeptide sequence encapsulated within a protective molecular cradle and an oxidant‐free route from selenenyl iodide (Sec–SeI) enable the isolation of Sec–SeOH. Contrary to the long‐
Ryosuke Masuda, Satoru Kuwano, Kei Goto
wiley   +2 more sources