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Selenium and Selenoproteins in Health
Selenium is a trace mineral that is essential for health. After being obtained from food and taken up by the liver, selenium performs various physiological functions in the body in the form of selenoproteins, which are best known for their redox activity and anti-inflammatory properties.
Fan Zhang, Xuelian Li, Yumiao Wei
openaire +3 more sources
It is known that seven mammalian selenoproteins are localized in the endoplasmic reticulum: SELENOM, SELENOT, SELENOF, SELENOK, SELENOS, SELENON, and DIO2.
Elena G. Varlamova +2 more
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Redox Active Motifs in Selenoproteins [PDF]
Selenoproteins use the rare amino acid selenocysteine (Sec) to act as the first line of defense against oxidants, which are linked to aging, cancer, and neurodegenerative diseases.
Arner, Elias S. J. +10 more
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Selenium Utilization Strategy by Microalgae
The diversity of selenoproteins raises the question of why so many life forms require selenium. Selenoproteins are found in bacteria, archaea, and many eukaryotes. In photosynthetic microorganisms, the essential requirement for selenium has been reported
Hiroya Araie, Yoshihiro Shiraiwa
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Role of selenium deficiency in pediatrics with acquired hypothyroidism
Background: Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies.
Hossein Moravej +7 more
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Selenium and selenoproteins in health and disease
The beneficial role of the trace element selenium (Se) in human health has been known for several decades and is attributed both to low-molecular-weight Se compounds and to its presence within 25 selenoproteins in the form of the amino acid ...
Khanna, KK +6 more
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Biosynthetic selenoproteins with genetically-encoded photocaged selenocysteines / [PDF]
Selenocysteine is a valuable component of both natural selenoproteins and designer biocatalysts; however the availability of such proteins is hampered by technical limitations.
Masevičius, Viktoras, +6 more
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Characterization of the aerosol produced by infrared femtosecond laser ablation of polyacrylamide gels for the sensitive inductively coupled plasma mass spectrometry detection of selenoproteins [PDF]
A 2D high repetition rate femtosecondlaserablation strategy (2-mm wide lane) previously developed for the detection of selenoproteins in gel electrophoresis by inductively coupled plasma mass spectrometry was found to increase signal sensitivity by a ...
Claverie, Fanny +11 more
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Biosynthesis, Engineering, and Delivery of Selenoproteins
Selenocysteine (Sec) was discovered as the 21st genetically encoded amino acid. In nature, site-directed incorporation of Sec into proteins requires specialized biosynthesis and recoding machinery that evolved distinctly in bacteria compared to archaea ...
David E. Wright, Patrick O’Donoghue
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Dietary selenium (Se)-compounds accumulated in plants are essential for human metabolism and normal physiological processes. Inorganic and organic Se species can be readily absorbed by the human body, but are metabolized differently and thus exhibit ...
Leonardo Warzea Lima +3 more
doaj +1 more source

