Results 31 to 40 of about 7,542 (180)

Selenium—More than Just a Fortuitous Sulfur Substitute in Redox Biology

Molecules, 2023
Living organisms use selenium mainly in the form of selenocysteine in the active site of oxidoreductases. Here, selenium’s unique chemistry is believed to modulate the reaction mechanism and enhance the catalytic efficiency of specific enzymes in ways ...
Luisa B. Maia, Biplab K. Maiti, Isabel Moura, José J. G. Moura   +3 more
doaj   +1 more source

Selenotranscriptome Network in Non-alcoholic Fatty Liver Disease

Frontiers in Nutrition, 2021
Observational studies indicate that selenium may contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Transcriptomic exploration of the aetiology and progression of NAFLD may offer insight into the role selenium plays in this ...
Kaitlin Day, Lucia A. Seale, Ross M. Graham, Barbara R. Cardoso   +3 more
doaj   +1 more source

Selenium and Selenoproteins in Health

Biomolecules, 2023
Selenium is a trace mineral that is essential for health. After being obtained from food and taken up by the liver, selenium performs various physiological functions in the body in the form of selenoproteins, which are best known for their redox activity and anti-inflammatory properties.
Fan Zhang, Xuelian Li, Yumiao Wei
openaire   +3 more sources

Selenium Utilization Strategy by Microalgae

Molecules, 2009
The diversity of selenoproteins raises the question of why so many life forms require selenium. Selenoproteins are found in bacteria, archaea, and many eukaryotes. In photosynthetic microorganisms, the essential requirement for selenium has been reported
Hiroya Araie, Yoshihiro Shiraiwa
doaj   +1 more source

The Role of Selenoproteins SELENOM and SELENOT in the Regulation of Apoptosis, ER Stress, and Calcium Homeostasis in the A-172 Human Glioblastoma Cell Line

Biology, 2022
It is known that seven mammalian selenoproteins are localized in the endoplasmic reticulum: SELENOM, SELENOT, SELENOF, SELENOK, SELENOS, SELENON, and DIO2.
Elena G. Varlamova, Michael V. Goltyaev, Egor A. Turovsky   +2 more
doaj   +1 more source

Role of selenium deficiency in pediatrics with acquired hypothyroidism

International Journal of Preventive Medicine, 2021
Background: Although selenium is one of the nutrients that has an important role in the metabolism of thyroid hormones, it has been investigated in rare studies.
Hossein Moravej, Shahrokh Rakhshandehroo, Homa Ilkhanipoor, Anis Amirhakimi, Khashayar Rostami, Negar Yazdani, Mozhgan Moghtaderi, Shokroallah Mazlumi-abrazgah   +7 more
doaj   +1 more source

The Relevance of Plant-Derived Se Compounds to Human Health in the SARS-CoV-2 (COVID-19) Pandemic Era

Antioxidants, 2021
Dietary selenium (Se)-compounds accumulated in plants are essential for human metabolism and normal physiological processes. Inorganic and organic Se species can be readily absorbed by the human body, but are metabolized differently and thus exhibit ...
Leonardo Warzea Lima, Serenella Nardi, Veronica Santoro, Michela Schiavon   +3 more
doaj   +1 more source

Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases

Frontiers in Nutrition, 2021
This review covers current knowledge of selenium in the dietary intake, its bioavailability, metabolism, functions, biomarkers, supplementation and toxicity, as well as its relationship with diseases and gut microbiota specifically on the symbiotic ...
Rannapaula Lawrynhuk Urbano Ferreira, Karine Cavalcanti Maurício Sena-Evangelista, Karine Cavalcanti Maurício Sena-Evangelista, Eduardo Pereira de Azevedo, Francisco Irochima Pinheiro, Francisco Irochima Pinheiro, Ricardo Ney Cobucci, Ricardo Ney Cobucci, Lucia Fatima Campos Pedrosa, Lucia Fatima Campos Pedrosa   +9 more
doaj   +1 more source

The effects of selenium on the translation efficiency of selenoproteins GPX1, GPX4, and TXNRD1 in oxLDL-induced EA.hy926 cells

Food Science and Human Wellness
Selenium is a crucial trace element that contributes to physiological processes in the body as selenoproteins. Selenoproteins serve as an integral role in the body in controlling the redox state of cells and protecting against damage induced by oxidative
Jiaqi Lu, Jing Meng, Yanzhi Lang, Abdul Rehman, Yamei Yan, Linwu Ran   +5 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source