Results 91 to 100 of about 19,390 (205)

Microtitre Plate Based Cell-SELEX Method

Bio-Protocol, 2018
Aptamers have emerged as a novel category in the field of bioreceptors due to their wide applications ranging from biosensing to therapeutics. Several variations of their screening process, called SELEX have been reported which can yield sequences with ...
Munish Shorie, Harmanjit Kaur
doaj   +1 more source

Monitoring the SELEX screening by ssFABS.

, 2019
Monitoring the SELEX screening by ssFABS.
Meng Zhao (54299), Kuancan Liu (3834220), Huiling Li (260350), Xiaopeng Lan (3834226), Weibin Li (331743)   +4 more
core   +1 more source

The genetics of SELEX

, 2013
SELEX is a robust technique for identifying nucleic acid aptamers with selectable characteristics. SELEX is a combinatorially tedious exhaustive search system, typically involving up to 1010 possible aptamers.
Kinghorn, AB, Tanner, JA
core  

Sequence families after 12 rounds of SELEX.

, 2016
Sequence families after 12 rounds of SELEX.
Yongqiang Yang (670525), Renshan Sun (3155361), Tao Yang (184280), Xinze Ran (296033)   +3 more
core   +1 more source

Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells

International Journal of Nanomedicine
Chao Cheng,1,* Minjia Sun,1– 3,* Jingjing Li,1,* Yitong Xue,1 Xia Cai,4 Jing Liu,1 Xiaolian Wang,5 Shouhong Xu,2 Youhua Xie,1 Junqi Zhang1 1MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease ...
Cheng C, Sun M, Li J, Xue Y, Cai X, Liu J, Wang X, Xu S, Xie Y, Zhang J   +9 more
doaj  

Percentage recovery of ssDNA using different SELEX methods.

, 2012
Both exonuclease- and T7-based methods were used to generate ssDNA, and counter-selection was preformed after round 3 (exonuclease-based SELEX) and 5 (T7-based SELEX).
Jacques Theron (129230), Lia S. Rotherham (129222), Makobetsa Khati (129233), Charlotte Maserumule (129226), Keertan Dheda (65382)   +4 more
core   +1 more source

Discrete Dynamical Systems in Multiple Target and Alternate SELEX [PDF]

, 2015
Dynamical systems are often used to model biochemical and biological processes. In Seo et al. (2010, 2014) we studied two mathematical models of the iterative biochemical procedure known as SELEX (Systematic Evolution of Ligands by EXponential Enrichment)
Seo, Yeon-Jung, Levine, Howard
core  

RNA Aptamers Targeting Integrin α5β1 as Probes for Cyto- and Histofluorescence in Glioblastoma

Molecular Therapy: Nucleic Acids, 2019
Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess several advantages, like their smaller size, temperature stability, ease of chemical modification, lack of immunogenicity and toxicity, and lower cost of production,
Pierre Fechter, Elisabete Cruz Da Silva, Marie-Cécile Mercier, Fanny Noulet, Nelly Etienne-Seloum, Dominique Guenot, Maxime Lehmann, Romain Vauchelles, Sophie Martin, Isabelle Lelong-Rebel, Anne-Marie Ray, Cendrine Seguin, Monique Dontenwill, Laurence Choulier   +13 more
doaj   +1 more source

SELEX-technology development in high-troughput

, 2012
Der SELEX-Prozess zur Selektion funktioneller Nukleinsäuren (hier: Aptamere) ist, obgleich mittlerweile vielfach modifiziert, noch immer ein zeit- und damit kostenintensives Verfahren.
Schütze, Tatjana
core   +1 more source

NMR monitoring of the SELEX process to confirm enrichment of structured RNA

Scientific Reports, 2017
RNA aptamers are RNA molecules that bind to a target molecule with high affinity and specificity using uniquely-folded tertiary structures. RNA aptamers are selected from an RNA pool typically comprising up to 1015 different sequences generated by ...
Ryo Amano, Kazuteru Aoki, Shin Miyakawa, Yoshikazu Nakamura, Tomoko Kozu, Gota Kawai, Taiichi Sakamoto   +6 more
doaj   +1 more source