Results 91 to 100 of about 12,731 (219)
Sequence families after 12 rounds of SELEX.
, 2016 Sequence families after 12 rounds of SELEX.
Yongqiang Yang (670525) +3 more
core +1 more source
Post‐transcriptional regulatory networks: The dynamic interplay of RNA‐binding proteins
The FEBS Journal, Volume 293, Issue 12, Page 3423-3441, June 2026.Post‐transcriptional gene expression regulation is controlled by RNA‐binding proteins (RBPs), which influence many processes including splicing, localization, translation, and decay. Rather than acting alone, RBPs bind RNAs combinatorially, forming complex, context‐dependent regulatory networks.
Lena A. Street +2 more
wiley +1 more source
International Journal of NanomedicineChao Cheng,1,* Minjia Sun,1– 3,* Jingjing Li,1,* Yitong Xue,1 Xia Cai,4 Jing Liu,1 Xiaolian Wang,5 Shouhong Xu,2 Youhua Xie,1 Junqi Zhang1 1MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease ...
Cheng C +9 more
doaj
RNA Aptamers Targeting Integrin α5β1 as Probes for Cyto- and Histofluorescence in Glioblastoma
Molecular Therapy: Nucleic Acids, 2019 Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess several advantages, like their smaller size, temperature stability, ease of chemical modification, lack of immunogenicity and toxicity, and lower cost of production,
Pierre Fechter +13 more
doaj +1 more source
Percentage recovery of ssDNA using different SELEX methods.
, 2012 Both exonuclease- and T7-based methods were used to generate ssDNA, and counter-selection was preformed after round 3 (exonuclease-based SELEX) and 5 (T7-based SELEX).
Jacques Theron (129230) +4 more
core +1 more source
Aptamer Screening: Current Methods and Future Trend towards Non-SELEX Approach
BiosensorsAptamers are nucleic acid sequences that specifically bind with target molecules and are vital to applications such as biosensing, drug development, disease diagnostics, etc.
Zhihui Fang +6 more
doaj +1 more source
NMR monitoring of the SELEX process to confirm enrichment of structured RNA
Scientific Reports, 2017 RNA aptamers are RNA molecules that bind to a target molecule with high affinity and specificity using uniquely-folded tertiary structures. RNA aptamers are selected from an RNA pool typically comprising up to 1015 different sequences generated by ...
Ryo Amano +6 more
doaj +1 more source
Simple Methods and Rational Design for Enhancing Aptamer Sensitivity and Specificity
Frontiers in Molecular Biosciences, 2018 Aptamers are structured nucleic acid molecules that can bind to their targets with high affinity and specificity. However, conventional SELEX (Systematic Evolution of Ligands by EXponential enrichment) methods may not necessarily produce aptamers of ...
Priya Kalra +6 more
doaj +1 more source
Gold Nanoparticles as a Platform for Small Molecule SELEX
, 2017 Small molecules play a significant role in a variety of applications. Current detection methods present limitations leaving an unmet need for alternative methods of detection.
Smith, McKenzie Rose
core +1 more source
Using Aptamers for Cancer Biomarker Discovery
Journal of Nucleic Acids, 2013 Aptamers are single-stranded synthetic DNA- or RNA-based oligonucleotides that fold into various shapes to bind to a specific target, which includes proteins, metals, and molecules.
Yun Min Chang +2 more
doaj +1 more source