Results 71 to 80 of about 20,710 (205)
The FEBS Journal, EarlyView.DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source
Reliability Investigation of GaN HEMTs for MMICs Applications
Micromachines, 2014 Results obtained during the evaluation of radio frequency (RF) reliability carried out on several devices fabricated with different epi-structure and field-plate geometries will be presented and discussed.
Alessandro Chini +4 more
doaj +1 more source
High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency. [PDF]
, 2016 The systemic evolution of ligands by exponential enrichment (SELEX) technique is a powerful and effective aptamer-selection procedure. However, modifications to the process can dramatically improve selection efficiency and aptamer performance.
Burnett, John C +6 more
core
Protein design and RNA design: Perspectives
Quantitative Biology, Volume 14, Issue 2, June 2026.Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley +1 more source
Aptamer-based Theranostics in Oncology: Design Strategies and Limitations
BIO IntegrationCancer remains a major global health burden, necessitating innovative approaches for improved diagnosis and treatment. Aptamer-based theranostics have gained attention in the field of cancer research and treatment.
Jyoti Trivedi +3 more
doaj +1 more source
Rapidly Neutralizable and Highly Anticoagulant Thrombin-Binding DNA Aptamer Discovered by MACE SELEX
Molecular Therapy: Nucleic Acids, 2019 We present a rapidly neutralizable and highly anticoagulant thrombin-binding aptamer with a short toehold sequence, originally discovered by systematic evolution of ligands by exponential enrichment (SELEX) with microbead-assisted capillary ...
Koji Wakui +7 more
doaj +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Ergot alkaloids (EAs), toxic secondary metabolites produced by Claviceps purpurea, pose food and feed safety concerns for cereal grains, particularly rye and wheat. While EAs are most frequently associated with rye, their occurrence in other cereals has been increasingly reported across diverse regions.
Chamali Kodikara +2 more
wiley +1 more source
New Configurations of Low-Cost Dual-Polarized Printed Antennas for UWB Arrays
International Journal of Antennas and Propagation, 2012 A novel class of structures is proposed to realize ultra-wide-band radiating elements for large arrays, providing dual polarization, beam scanning, and compact and inexpensive realization based on suitable rhombic arrangements of dipoles printed on low ...
Guido Valerio +4 more
doaj +1 more source
Journal of Food Science, Volume 91, Issue 5, May 2026.ABSTRACT Biogenic amines, primarily histamine, cadaverine, and putrescine, are important indicators of microbial spoilage and potential health risks. This review summarizes established and novel analytical methods for quantitatively determining biogenic amines in fish and fish products, along with their limits of detection in these complex matrices ...
Lasse Petersen
wiley +1 more source
Advantages, applications, and future directions of in vivo aptamer SELEX: A review
Molecular Therapy: Nucleic AcidsIn vivo systematic evolution of ligands by exponential enrichment (SELEX) emerged as a transformative technique for directly identifying aptamers within living organisms.
Minchuan Lyu +4 more
doaj +1 more source