Results 71 to 80 of about 12,731 (219)

Trends in nucleotide frequencies of the Neutral SELEX and Hfq SELEX pools.

open access: yes, 2013
Each group in the bar charts shows the difference in mononucleotide frequency (A) and dinucleotide frequency (B) from the averages of the E. coli K-12 genome.
Doris Chen (367236)   +4 more
core   +1 more source

autosome-ru/PWM-evaluation-using-SNP-SELEX: PWM evaluation using SNP-SELEX

open access: yes, 2021
<p>Extended data for "Positional weight matrices have sufficient prediction power for analysis of noncoding variants".</p ...
Sergey Abramov
core   +1 more source

Implantable electrochemical sensors for continuous blood monitoring

open access: yesFlexMat, EarlyView.
Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou   +3 more
wiley   +1 more source

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam   +4 more
wiley   +1 more source

A Highlight of Recent Advances in Aptamer Technology and Its Application

open access: yesMolecules, 2015
Aptamers and SELEX (systematic evolution of ligands by exponential enrichment) technology have gained increasing attention over the past 25 years. Despite their functional similarity to protein antibodies, oligonucleotide aptamers have many unique ...
Hongguang Sun, Youli Zu
doaj   +1 more source

SELEX RICH performance and physics results [PDF]

open access: yes, 2002
SELEX took data in the 1996/7 Fixed Target Run at Fermilab. The excellent performance parameters of the SELEX RICH Detector had direct influence on the quality of the obtained physics ...
al., Jurgen Engelfried et
core  

Effects of SELEX on structural stability of RNA sequences.

open access: yes, 2013
(A) Average Z-score of sequences in the initial library (brown bar), each pool of Neutral SELEX (green bars) and the sequences from the Hfq Genomic SELEX experiment after 9 rounds of selection (grey bar). Numbers indicate the SELEX cycle.
Doris Chen (367236)   +4 more
core   +1 more source

The optimization of cell-SELEX based aptamer selection through masking DNA, PCR and non-SELEX [PDF]

open access: yes, 2013
Aptamers are short oligonucleotide sequences that are capable of binding with high affinity and specificity to a wide variety of targets. The selection of aptamers from a random oligonucleotide library, by cell-SELEX, has lead to their in vivo ...
Obrecht, Natalia
core  

Effectiveness of SELEX tests in silico.

open access: yes, 2022
Effectiveness of SELEX tests in silico.
Ekaterina M. Myasnikova (12008895)   +1 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

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