Results 61 to 70 of about 12,731 (219)
A novel artificial intelligence-based approach for identification of deoxynucleotide aptamers.
PLoS Computational Biology, 2021 The selection of a DNA aptamer through the Systematic Evolution of Ligands by EXponential enrichment (SELEX) method involves multiple binding steps, in which a target and a library of randomized DNA sequences are mixed for selection of a single ...
Frances L Heredia +2 more
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Schematic of Adherent Cell-SELEX (AC-SELEX) Procedure.
, 2013 A starting library of >1015 aptamers was utilized and eighteen rounds of AC-SELEX were carried out to purify and amplify the aptamers which recognized epitopes present on HF cells and not present on HeLa cells.
Jessica C. Graham (325676) +1 more
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Bio-SELEX: A Strategy for Biomarkers Isolation Directly from Biological Samples
Methods and Protocols, 2023 Bio-SELEX is a revolutionary method for the discovery of novel biomarkers within biological samples, offering profound insights into diagnosing both infectious and non-infectious diseases.
Juan David Ospina-Villa +2 more
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Aptamers and SELEX in Chemistry & Biology
Chemistry & Biology, 2014 Nucleic acid aptamers, or simply aptamers, are oligonucleotides that bind specific ligands that vary from small molecules to proteins. An aptamer for a specific ligand is routinely identified through the process of systematic evolution of ligands by exponential enrichment, although some aptamers are found in nature as ligand-binding sites of special ...
Famulok, M., Mayer, G.
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Soups & SELEX for the origin of life [PDF]
RNA, 2015 The theory of evolution quickly brought up the most fascinating question in biology: the origin of life. How did life emerge? The biggest challenge in this endeavor to understand how life could have emerged without a controller is to unravel the chemical processes that made the synthesis of complex molecules containing information possible.
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Reliability Investigation of GaN HEMTs for MMICs Applications
Micromachines, 2014 Results obtained during the evaluation of radio frequency (RF) reliability carried out on several devices fabricated with different epi-structure and field-plate geometries will be presented and discussed.
Alessandro Chini +4 more
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Aptamer-based Theranostics in Oncology: Design Strategies and Limitations
BIO IntegrationCancer remains a major global health burden, necessitating innovative approaches for improved diagnosis and treatment. Aptamer-based theranostics have gained attention in the field of cancer research and treatment.
Jyoti Trivedi +3 more
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Rapidly Neutralizable and Highly Anticoagulant Thrombin-Binding DNA Aptamer Discovered by MACE SELEX
Molecular Therapy: Nucleic Acids, 2019 We present a rapidly neutralizable and highly anticoagulant thrombin-binding aptamer with a short toehold sequence, originally discovered by systematic evolution of ligands by exponential enrichment (SELEX) with microbead-assisted capillary ...
Koji Wakui +7 more
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New Configurations of Low-Cost Dual-Polarized Printed Antennas for UWB Arrays
International Journal of Antennas and Propagation, 2012 A novel class of structures is proposed to realize ultra-wide-band radiating elements for large arrays, providing dual polarization, beam scanning, and compact and inexpensive realization based on suitable rhombic arrangements of dipoles printed on low ...
Guido Valerio +4 more
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, 2016 UROP report and poster, Spring 2016, BiologyUndergraduate Research Opportunities Program, University of Minnesota DuluthRyan, Courtney; Lacher, Sarah E; Slattery, Matthew. (2016). SELEX-sequencing. Retrieved from the University Digital Conservancy, https:
Slattery, Matthew +2 more
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