Results 81 to 90 of about 19,390 (205)
Plant Biotechnology Journal, Volume 24, Issue 10, Page 5440-5459, October 2026.ABSTRACT Drought stress severely restricts rice productivity, necessitating strategies to enhance stress resilience. Here, we identify translation termination as a tunable regulatory node for stress adaptation. Using 25 rounds of SELEX, we isolated RTAR, an RNA aptamer that binds the rice eukaryotic release factor 1 (OseRF1) with nanomolar affinity ...
Shuangfeng Dai +7 more
wiley +1 more source
SELEX RICH performance and physics results [PDF]
, 2002 SELEX took data in the 1996/7 Fixed Target Run at Fermilab. The excellent performance parameters of the SELEX RICH Detector had direct influence on the quality of the obtained physics ...
al., Jurgen Engelfried et
core
The optimization of cell-SELEX based aptamer selection through masking DNA, PCR and non-SELEX [PDF]
, 2013 Aptamers are short oligonucleotide sequences that are capable of binding with high affinity and specificity to a wide variety of targets. The selection of aptamers from a random oligonucleotide library, by cell-SELEX, has lead to their in vivo ...
Obrecht, Natalia
core
ChemBioChem, Volume 27, Issue 18, 28 September 2026.A 4′‐thiouridine phosphoramidite was prepared and site‐selectively incorporated into PTEN‐targeting gapmer ASOs. Flank‐modified gapmers with defined phosphorothioate linkage patterns maintained potent target knockdown under transfection and gymnotic delivery, matching 2′‐O‐methoxyethyl comparators and highlighting 4′‐thioribose as a valuable motif for ...
Joanna E. Parkes +10 more
wiley +1 more source
Effectiveness of SELEX tests in silico.
, 2022 Effectiveness of SELEX tests in silico.
Ekaterina M. Myasnikova (12008895) +1 more
core +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source
Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine
International Journal of Molecular Sciences, 2017 Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with high affinity and specificity. The process of selecting an aptamer is called Systematic Evolution of Ligands by Exponential Enrichment (SELEX).
Zhenjian Zhuo +9 more
semanticscholar +1 more source
Accelerating Post-SELEX Aptamer Engineering Using Exonuclease Digestion
Journal of the American Chemical Society, 2020 The systematic evolution of ligands by exponential enrichment (SELEX) process enables the isolation of aptamers from random oligonucleotide libraries. However, it is generally difficult to identify the best aptamer from the resulting sequences, and the ...
Juan Canoura +5 more
semanticscholar +1 more source
A Highlight of Recent Advances in Aptamer Technology and Its Application
Molecules, 2015 Aptamers and SELEX (systematic evolution of ligands by exponential enrichment) technology have gained increasing attention over the past 25 years. Despite their functional similarity to protein antibodies, oligonucleotide aptamers have many unique ...
Hongguang Sun, Youli Zu
doaj +1 more source
Effects of SELEX on structural stability of RNA sequences.
, 2013 (A) Average Z-score of sequences in the initial library (brown bar), each pool of Neutral SELEX (green bars) and the sequences from the Hfq Genomic SELEX experiment after 9 rounds of selection (grey bar). Numbers indicate the SELEX cycle.
Doris Chen (367236) +4 more
core +1 more source