The roles of the nerve-immune axis in modulating bone regeneration. [PDF]
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Neuropilin-1 expression in primary and metastatic prostate cancer: Expression patterns and clinicopathological correlations. [PDF]
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CytoSignal detects locations and dynamics of ligand-receptor signaling at cellular resolution from spatial transcriptomic data. [PDF]
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Immune-neural regulatory mechanism of osteoporosis induced by androgen deficiency. [PDF]
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Global mapping of RNA N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) in human subcutaneous and visceral adipose tissue reveals novel targets that correlate with clinical variables of obesity. [PDF]
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Effects of Long-Term Moderate-Intensity Exercise on Autonomic Nervous System Dysfunction Induced by Cardiac Neurovascular Interface Deterioration. [PDF]
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Sema3A regulates bone-mass accrual through sensory innervations
Nature, 2013Semaphorin 3A (Sema3A) is a diffusible axonal chemorepellent that has an important role in axon guidance. Previous studies have demonstrated that Sema3a(-/-) mice have multiple developmental defects due to abnormal neuronal innervations. Here we show in mice that Sema3A is abundantly expressed in bone, and cell-based assays showed that Sema3A affected ...
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Clinical Immunology, 2022Immune semaphorins are widely accepted to have functional impact on autoimmune diseases.To assess the status of sema3A and sema4A in the pathogenesis of Multiple Sclerosis (MS).Sema3A expression on (T regulatory cells)Tregs was decreased in MS patients, compared to healthy controls (35.85 ± 16.7% vs 88.27 ± 3.8%; p ≤ 0.001). Serum levels of sema3A were
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The role of Wnt, ARL4C, and Sema3A in developmental process and disease pathogenesis
Pathology International, 2023AbstractVarious types of tumors, including malignant and benign ones, occur in the oral cavity. These arise from the mucosal epithelium, odontogenic epithelium, and salivary gland. To date, few major driver events in oral tumors have been identified. Accordingly, molecular targets in anti‐tumor therapy for oral tumors are lacking.
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