Results 41 to 50 of about 6,782 (204)

Sema3A promotes the resolution of cardiac inflammation after myocardial infarction [PDF]

, 2017
Optimal healing after myocardial infarction requires not only the induction of inflammation, but also its timely resolution. In patients, 30 days post myocardial infarction, circulating monocytes have increased expression of Semaphorin3A (Sema3A) as ...
Heymans, Stephane, Vanhaverbeke, Maarten, Rienks, M., Nicole Bitsch, Verjans, J., Carai, P., Marieke Rienks, Stephane Heymans, Carai, Paolo, Rienks, Marieke, Bitsch, Nicole, Papageorgiou, Anna, Heymans, S., Cuijpers, Ilona, Anna Papageorgiou, Cuijpers, I., Vanhaverbeke, M., Maarten Vanhaverbeke, Verjans, Johan, Bitsch, N., Mark Schellings, Papageorgiou, A., Johan Verjans, Schellings, Mark, Schellings, M., Ilona Cuijpers, Paolo Carai   +26 more
core   +1 more source

Semaphorin-3A as An Immune Modulator Is Suppressed by MicroRNA-145-5p

Cell Journal, 2018
Objective Semaphorin-3A (SEMA3A) and its receptors are found on some immune cells and act as suppressors of immune cells over-activation. Considering the role of SEMA3A and its down-regulation in some autoimmune diseases, as well as our bioinformatics ...
Mahsa Rezaeepoor, Mazdak Ganjalikhani-hakemi, Shima Shapoori, Nahid Eskandari, Mohammadreza Sharifi, Masoud Etemadifar, Marjan Mansourian   +6 more
doaj   +1 more source

Semaphorin3A induces nerve regeneration in the adult cornea-a switch from its repulsive role in development. [PDF]

PLoS ONE, 2018
The peripheral sensory nerves that innervate the cornea can be easily damaged by trauma, surgery, infection or diabetes. Several growth factors and axon guidance molecules, such as Semaphorin3A (Sema3A) are upregulated upon cornea injury.
Min Zhang, Qiang Zhou, Yuncin Luo, Tara Nguyen, Mark I Rosenblatt, Victor H Guaiquil   +5 more
doaj   +1 more source

Semaphorin3A Exacerbates Cardiac Microvascular Rarefaction in Pressure Overload‐Induced Heart Disease

Advanced Science, 2023
Microvascular endothelial cells (MiVECs) impair angiogenic potential, leading to microvascular rarefaction, which is a characteristic feature of chronic pressure overload‐induced cardiac dysfunction.
Chaofu Li, Yongchao Zhao, Fuhai Li, Zimu Wang, Zhimei Qiu, Yukun Yang, Weidong Xiong, Rui Wang, Han Chen, Fei Xu, Tongtong Zang, Zhiqiang Pei, Yan Wang, Bei Shi, Li Shen, Junbo Ge   +15 more
doaj   +1 more source

Sema3A expression.

, 2013
A. Reduced Sema3A expression in the lungs of Sema3A-/- mice was assessed using qPCR. B. Representative AP-Nrp-1ecto binding in tissue sections from Sema3A+/+ (middle panels) and Sema3A-/- mice (bottom panels) at P1 (left) and P28 (right).
Michael J. Delannoy (339732), Patrice M. Becker (339730), Tracy S. Tran (339731), Chaoxia He (339733), John M. Shannon (339734), Sharon McGrath-Morrow (216731)   +5 more
core   +1 more source

Osseointegration of Titanium Implants in a Botox-Induced Muscle Paralysis Rat Model Is Sensitive to Surface Topography and Semaphorin 3A Treatment

Biomimetics, 2023
Reduced skeletal loading associated with many conditions, such as neuromuscular injuries, can lead to bone fragility and may threaten the success of implant therapy.
Jingyao Deng, D. Joshua Cohen, Michael B. Berger, Eleanor L. Sabalewski, Michael J. McClure, Barbara D. Boyan, Zvi Schwartz   +6 more
doaj   +1 more source

Localization of Sema3A protein.

, 2016
Representative micrographs of Sema3A staining in presumptive SCs, located in the satellite position on fibers (arrow indicates nucleus) in control and Supraspinatus (SS) muscle explant cultures at baseline (without ISDN treatment) or with ISDN (as ...
Jeff R. S. Leiter (3138747), Jason Peeler (804755), Peter B. MacDonald (3138744), Judy E. Anderson (602914), Deanna Gigliotti (3138741)   +4 more
core   +1 more source

Growth cone collapse assay of the SEMA3A^WT, SEMA3A^I334V, or control.

, 2013
The percent of collapsed growth cones of the E8 chick embryos incubated with medium containing vector only, SEMA3AWT, or SEMA3AI334V at dilutions (0.03, 0.1, and 0.3) of a concentrated media.
Ichiro Watanabe (401861), Daiki Miki (128628), Kazuaki Chayama (128675), Kenta Kajihara (401854), Takeshi Aiba (401864), Masaaki Toshishige (401848), Yasuki Kihara (401869), Yuko Uchimura-Makita (401853), Noboru Oda (401851), Satoshi Tashiro (238874), Chikaaki Motoda (401856), Yukihiko Yoshida (401859), Yoshikazu Watanabe (401858), Kazuyoshi Suenari (401852), Yasufumi Hayashida (401849), Seiko Ohno (401866), Hidenori Ochi (128649), Takehito Tokuyama (401850), Minoru Horie (401867), Kimie Ohkubo (401860), Akinori Sairaku (401855), Mai Fujiwara (401857), C. Nelson Hayes (128614), Akihiko Nogami (401862), Naoto Endo (325630), Hidekazu Suzuki (105870), Wataru Shimizu (401865), Yukiko Nakano (401847), Naomasa Makita (401868), Koji Arihiro (56456), Kanae Hasegawa (401863), Hiroshi Watanabe (81742)   +31 more
core   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source