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Biochemical Pharmacology
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, creating an urgent need to identify new therapeutic targets. Semaphorin 7A (SEMA7A), a glycosylphosphatidylinositol (GPI)-anchored protein, has been implicated in tumor progression, but its role in CRC, tumor microenvironment (TME), and inflammation-related CRC remains ...
Ling-Li, Zhang +3 more
exaly +3 more sources
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, creating an urgent need to identify new therapeutic targets. Semaphorin 7A (SEMA7A), a glycosylphosphatidylinositol (GPI)-anchored protein, has been implicated in tumor progression, but its role in CRC, tumor microenvironment (TME), and inflammation-related CRC remains ...
Ling-Li, Zhang +3 more
exaly +3 more sources
The Journal of Immunology, 2009
Abstract Semaphorins are a family of membrane-bound and secreted signaling molecules with active roles in nearly every organ system in processes ranging from heart morphogenesis to tumor development. We are investigating the potential roles of these molecules during T cell development in the thymus.
Devavani Chatterjea +2 more
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Abstract Semaphorins are a family of membrane-bound and secreted signaling molecules with active roles in nearly every organ system in processes ranging from heart morphogenesis to tumor development. We are investigating the potential roles of these molecules during T cell development in the thymus.
Devavani Chatterjea +2 more
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Abstract P3-03-23: Targeting of SEMA7A Signaling Improves Response to Endocrine Therapy in ER+ BC
Clinical Cancer ResearchAbstract Estrogen receptor-positive (ER+) breast cancer (BC) comprises over 70% of all breast cancers and is the leading cause of BC-related deaths in women worldwide. Despite available therapies against ER+ BC, recurrence inevitably arises, primarily due to therapeutic resistance.
Rachel Steinmetz +2 more
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A novel heterozygous intron mutation in SEMA7A causing kallmann syndrome in a female
Gynecological Endocrinology, 2020Yongting Zhao, Lihong Wang, Hui Che
exaly
LncRNA LOXL1‐AS1/miR‐28‐5p/SEMA7A axis facilitates pancreatic cancer progression
Cell Biochemistry and Function, 2020Yongcun Liu, Cheng Guo, Liping Wu
exaly
Sema7A, a brain immune regulator, regulates seizure activity in PTZ‐kindled epileptic rats
CNS Neuroscience and Therapeutics, 2020Jing Deng, Tao Xu
exaly
763 – The Homozygous P.R148W Mutation in Semaphorin 7A (SEMA7A) Causes a Novel Liver Disease
Gastroenterology, 2019Jiaquan Qu +5 more
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The molecular diversity of Sema7A, the semaphorin that carries the JMH blood group antigens
Transfusion, 2007Axel Seltsam +2 more
exaly
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2021
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