Results 81 to 90 of about 4,062 (156)

Single-cell fixed RNA profiling uncovers SEMA4D and LMCD1 as therapeutic targets in a liver fibrosis model

JHEP Reports
Background & Aims: Single-cell fixed RNA profiling (FLEX) is a novel technique that captures RNA expression in frozen tissues at a single-cell resolution.
Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Tran Van Bao, Nguyen Thi Ha, Pham Tuan Anh, Hiroko Ikenaga, Hideki Fujii, Kanako Yoshida, Masaru Enomoto, Sawako Uchida-Kobayashi, Hideto Yuasa, Tsutomu Matsubara, Vu Thuong Huyen, Yi Cheng, Ryota Yamagishi, Naoko Ohtani, Daisuke Oikawa, Fuminori Tokunaga, Tatiana Kisseleva, David A. Brenner, Yasuko Iwakiri, Jordi Gracia-Sancho, Norifumi Kawada   +23 more
doaj   +1 more source

Semaphorin 4D induced inhibitory synaptogenesis decreases epileptiform activity and alters progression to Status Epilepticus in mice. [PDF]

Epilepsy Res, 2023
Adel SS, Clarke VRJ, Evans-Strong A, Maguire J, Paradis S.   +4 more
europepmc   +1 more source

Dual-Function Semaphorin 4D Released by Platelets: Suppression of Osteoblastogenesis and Promotion of Osteoclastogenesis. [PDF]

Int J Mol Sci, 2022
Shindo S, Savitri IJ, Ishii T, Ikeda A, Pierrelus R, Heidari A, Okubo K, Nakamura S, Kandalam U, Rawas-Qalaji M, Leon E, Pastore MR, Hardigan P, Kawai T.   +13 more
europepmc   +1 more source

Anti-Semaphorin 4D Rescues Motor, Cognitive, and Respiratory Phenotypes in a Rett Syndrome Mouse Model. [PDF]

Int J Mol Sci, 2021
Mao Y, Evans EE, Mishra V, Balch L, Eberhardt A, Zauderer M, Gold WA.   +6 more
europepmc   +1 more source

Locally Secreted Semaphorin 4D Is Engaged in Both Pathogenic Bone Resorption and Retarded Bone Regeneration in a Ligature-Induced Mouse Model of Periodontitis. [PDF]

Int J Mol Sci, 2022
Ishii T, Ruiz-Torruella M, Yamamoto K, Yamaguchi T, Heidari A, Pierrelus R, Leon E, Shindo S, Rawas-Qalaji M, Pastore MR, Ikeda A, Nakamura S, Mawardi H, Kandalam U, Hardigan P, Witek L, Coelho PG, Kawai T.   +17 more
europepmc   +1 more source

Histological pattern of tumor inflammation and stromal density correlate with patient demographics and immuno-oncologic transcriptional profile in oral squamous cell carcinoma

Frontiers in Oral Health
IntroductionOral squamous cell carcinoma (OSCC) is the most prevalent oral malignancy, with emerging interest in the characterization of its tumor microenvironment.
Vasileios Ionas Theofilou, Ioana Ghita, Manar Elnaggar, Risa Chaisuparat, John C. Papadimitriou, Soren M. Bentzen, Soren M. Bentzen, Soren M. Bentzen, Donita Dyalram, Donita Dyalram, Joshua E. Lubek, Joshua E. Lubek, Robert A. Ord, Robert A. Ord, Rania H. Younis, Rania H. Younis   +15 more
doaj   +1 more source

Tenofovir Modulates Semaphorin 4D Signaling and Regulates Bone Homeostasis, Which Can Be Counteracted by Dipyridamole and Adenosine A2A Receptor. [PDF]

Int J Mol Sci, 2021
Llamas-Granda P, Martin-Rodríguez L, Largo R, Herrero-Beaumont G, Mediero A.   +4 more
europepmc   +1 more source

Differences in immune-related semaphorin levels in the CSF and serum of newly diagnosed, treatment-naive patients with relapsing–remitting multiple sclerosis: a case–control study

Frontiers in Neurology
BackgroundThe pathogenesis of multiple sclerosis (MS) remains incompletely elucidated. Semaphorins play an active role in the immune and nervous systems by regulating receptor-mediated adhesion mechanisms.
Furkan Sarıdaş, Birnur Aydın, Rifat Özpar, Emine Rabia Koç, Bahattin Hakyemez, Tülin Alkan, Ömer Faruk Turan   +6 more
doaj   +1 more source

Semaphorin 4D is a potential biomarker in pediatric leukemia and promotes leukemogenesis by activating PI3K/AKT and ERK signaling pathways. [PDF]

Oncol Rep, 2021
Jiang H, Tang J, Qiu L, Zhang Z, Shi S, Xue L, Kui L, Huang T, Nan W, Zhou B, Zhao C, Yu M, Sun Q.   +12 more
europepmc   +1 more source

Semaphorin-4D [PDF]

, 2020
openaire   +1 more source