Results 81 to 90 of about 4,278 (174)
, 2022 Peptic ulcer disease is a frequent clinical problem with potentially serious complications such as bleeding or perforation. A decisive factor in the pathogenesis of peptic ulcers is gastric acid, the secretion of which is controlled by the hormone ...
Olsen, August A. +41 more
core +2 more sources
Recent Advances in Natural Polymers‐based Hydrogels for Periodontal Regeneration
Macromolecular Bioscience, Volume 26, Issue 5, May 2026.Natural polymer‐based hydrogels are emerging as promising biomimetic platforms for periodontal regeneration. This review highlights advances in alginate, collagen, and chitosan hydrogels engineered to modulate inflammation, deliver bioactive agents, and support tissue repair.
João de Freitas Gomes Neto +7 more
wiley +1 more source
Evaluating Protein Enrichment Methods to Improve Biomarker Discovery in Equine Cerebrospinal Fluid
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.Here, we compared two protein enrichment methods—ProteoMiner Small‐Capacity and PreOmics Enrich‐iST—for proteomic analysis of equine cerebrospinal fluid (CSF). PreOmics Enrich‐iST achieved superior depletion of high‐abundance proteins and identified a greater number of low‐abundance, neuropathology‐relevant proteins than ProteoMiner or native digestion.
Foti Federico +5 more
wiley +1 more source
Increased levels of plasma soluble Sema4D in patients with heart failure. [PDF]
PLoS ONE, 2013 Semaphorin 4D (Sema4D/CD100) is a 150-kDa transmembrane glycoprotein expressed by platelets and T-cells. When these cells are activated, Sema4D is cleaved proteolytically, generating a biologically active 120-kDa fragment (soluble Sema4D) capable of ...
Qiongyu Lu +12 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Abstract INTRODUCTION Alzheimer's disease (AD) exhibits high genetic and clinical heterogeneity that limits therapeutic success. Patient‐derived brain organoids and their extracellular vesicles (EVs) provide physiologically relevant models to study disease mechanisms and individualized drug responses.
Rachel J. Boyd +10 more
wiley +1 more source
Structure determination of human semaphorin 4D as an example of the use of MAD in non-optimal cases.
, 2006 Semaphorins are an important class of signalling molecules involved in axon guidance, immune function and angiogenesis. They are characterized by having an extracellular sema domain of about 500 residues.
Jones, EY +12 more
core +1 more source
MiR-214 suppressed ovarian cancer and negatively regulated semaphorin 4D
Tumor Biology, 2015 Ovarian cancer is one of the most common human malignancies in women. MiR-214 and semaphorin 4D (sema 4D) were found to be abhorrently expressed and involved in the progress of several kinds of malignant cancers. This study is aimed to investigate the cellular role of miR-214 and demonstrate that miR-214 negatively regulated sema 4D in ovarian cancer ...
Yang, Liu +7 more
openaire +2 more sources
Cancer Cell International, 2021 Background The hsa_circ_0004771 derived from NRIP1 (called circ_NRIP1) is a recently identified oncogenic circRNA. Here, we intended to investigate the role and mechanism of circ_NRIP1 in esophageal squamous cell carcinoma (ESCC), a prevalent and ...
Shifan Zhou +4 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.ORMDL proteins in the endoplasmic reticulum (ER) negatively regulate serine palmitoyltransferase (SPT) activity in response to the rate of de novo sphingolipid synthesis. Disruption of ceramide homeostasis by myriocin or fumonisin B1 (FB1) appears to destabilize the ORMDL‐SPT complex, leading to ORMDL degradation as a feedback mechanism.
Michal Mrkacek +7 more
wiley +1 more source
Expression of semaphorins-4D, -6D, -3C and -7A in hepatitis C virus infection [PDF]
, 2017 Virus hepatitisa C (HCV) je RNA virus iz porodice Flaviviridae, rod Hepacivirus, koji uzrokuje akutne i kronične bolesti jetre uključujući kronični hepatitis, cirozu te hepatocelularni karcinom.
Ljubić, Sven
core