Insight into Glyproline Peptides' Activity through the Modulation of the Inflammatory and Neurosignaling Genetic Response Following Cerebral Ischemia-Reperfusion. [PDF]
Glyprolines are Gly-Pro (GP)- or Pro-Gly (PG)-containing biogenic peptides. These peptides can act as neutrophil chemoattractants, or atheroprotective, anticoagulant, and neuroprotective agents.
Stavchansky VV +9 more
europepmc +2 more sources
Synthetic Adrenocorticotropic Peptides Modulate the Expression Pattern of Immune Genes in Rat Brain following the Early Post-Stroke Period. [PDF]
Ischemic stroke is an acute local decrease in cerebral blood flow due to a thrombus or embolus. Of particular importance is the study of the genetic systems that determine the mechanisms underlying the formation and maintenance of a therapeutic window (a
Filippenkov IB +7 more
europepmc +2 more sources
Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats. [PDF]
Cerebral ischaemia is the most common cause of impaired brain function. Biologically active peptides represent potential drugs for reducing the damage that occurs after ischaemia. The synthetic melanocortin derivative, ACTH(4-7)PGP (Semax), has been used
Filippenkov IB +10 more
europepmc +2 more sources
Morphological Features Of Lymphoid Structures Of Rat Inguinal Lymph Nodes In State Of Emotional Stress With Preliminary Injection Of Oligopeptides [PDF]
The lymphoid structures of inguinal lymph nodes and cells of the peripheral blood of 104 Vistar male rats of both experimental and control groups have been investigated by means of modern hystological and immunohystochemical methods. It has been revealed
А.А. Bakhmet
doaj +2 more sources
Antistress Action of Melanocortin Derivatives Associated with Correction of Gene Expression Patterns in the Hippocampus of Male Rats Following Acute Stress. [PDF]
Natural melanocortins (MCs) have been used in the successful development of drugs with neuroprotective properties. Here, we studied the behavioral effects and molecular genetic mechanisms of two synthetic MC derivatives-ACTH(4–7)PGP (Semax) and ACTH(6–9 ...
Filippenkov IB +9 more
europepmc +2 more sources
Integrating hybrid active‐passive communications into cognitive radio can achieve a spectrum‐ and energy‐efficiency information transmission, while the resource allocation has not been well studied particularly for the network with multiple secondary users (also termed as the Internet of Things (IoT) users).
Jianjun Luo +3 more
wiley +1 more source
In modern physiology, the priority direction is the study of the influence of various types of stress, leading, as a rule, to the development of depressive states, on the physiological systems of the body.
V. Kh. Murtalieva +4 more
doaj +1 more source
Blood vessels and neurons grow along one another and can influence each other's maturation, both during embryonic development and regeneration in adulthood. Understanding the molecular processes behind these events could improve current treatments for neurovascular disorders.
Idoia Elorza Ridaura +2 more
wiley +1 more source
Visualizing the Active Paths in Morphologically Defective Organic Thin‐Film Transistors
The effective current paths in an organic thin‐film transistor are visualized using dynamic surface potential in‐situ generated by ultra‐low voltage scanning electron microscopy. Nano‐ to micro‐scaled morphological defects blocking charge flow between contacts are recognized and thus, the as‐measured charge–carrier mobilities are corrected.
Wen‐Shan Zhang +7 more
wiley +1 more source
Comparative chemoreactome analysis of mexidol [PDF]
The paper presents the results of chemorectome modeling of the pharmacological effects of ethylmethylhydroxypyridine succinate (mexidol) as compared to control molecules (choline alfoscerate, piracetam, glycine, semax). Chemoreactome analysis showed that
I. J. Torshin +4 more
doaj +1 more source

