Results 81 to 90 of about 1,805,611 (181)

The deamination of n-pentylamine by monoamine oxidase and a semicarbazide-sensitive amine oxidase of rat heart

, 1983
n-Pentylamine is deaminated by homogenates of rat heart. Clorgyline inhibition curves at 10 and 100 μM n-pentylamine indicated that this substrate was deaminated by MAO-A, -B and a clorgyline-resistant amine oxidase sensitive to inhibition by ...
Margherita Strolin Benedetti, Christopher J Fowler, Christian Guffroy   +2 more
core   +1 more source

Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes.

, 2007
International audienceA strong induction of semicarbazide-sensitive amine oxidase (SSAO) has previously been reported during murine preadipocyte lineage differentiation but it remains unknown whether this emergence also occurs during adipogenesis in man.
Lefort, Corinne, Zorzano, Antonio, Carpéné, Christian, Philippe Valet, Antonio Zorzano, Corinne Lefort, Daviaud, Danièle, Sandra Gres, Bour, Sandy, Wabitsch, Martin, Christian Carpéné, Danièle Daviaud, Danielle Prévot, Prévot, Danielle, Gres, Sandra, Valet, Philippe, Saulnier-Blache, Jean-Sébastien, Sandy Bour, Jean-Sébastien Saulnier-Blache, Martin Wabitsch   +19 more
core   +1 more source

Semicarbazide-Sensitive Amine Oxidase in Vascular Smooth Muscle Cells

, 2002
Cultured vascular smooth muscle cells (VSMCs) derived from rat aortic media were used to examine semicarbazide-sensitive amine oxidase (SSAO) expression during their differentiation process.
Khadija El Hadri, Jacques Pairault, Marthe Moldes, Marise Andreani, Andreani, Marise, Bruno Feve, Nathalie Mercier, Mercier, Nathalie, El Hadri, Khadija, Pairault, Jacques, Feve, Bruno, Moldes, Marthe   +11 more
core   +1 more source

The Substrate Specificity of Purified Rat Lung Semicarbazide-Sensitive Amine Oxidase

, 2009
Objectives: The aim of this study was to investigate the substrate specificity of purified rat lung semicarbazide-sensitive amine ...
UÇAR, GÜLBERK, YABANOĞLU ÇİFTÇİ, SAMİYE   +1 more
core  

Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model

Frontiers in Pharmacology
IntroductionMonoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol ...
Ádám István Horváth, Ádám István Horváth, Kata Bölcskei, Nikolett Szentes, Nikolett Szentes, Nikolett Szentes, Éva Borbély, Éva Borbély, Valéria Tékus, Valéria Tékus, Valéria Tékus, Bálint Botz, Kitti Rusznák, Kitti Rusznák, Anett Futácsi, Anett Futácsi, Boldizsár Czéh, Boldizsár Czéh, Péter Mátyus, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes   +23 more
doaj   +1 more source

Synthesis of ortho-Functionalized 4-Aminomethylpyridazines as Substrate-Like Semicarbazide-Sensitive Amine Oxidase Inhibitors

, 2010
A series of 4-aminomethylpyridazines and -pyridazin-3(2H)-ones (“diaza-benzylamines”), bearing alkylamino side chains in ortho position relative to the CH2NH2 unit, was synthesized by catalytic hydrogenation of the corresponding nitriles in strongly ...
Hochholdinger, Iris (University of Vienna), Mátyus, Péter (Semmelweis Medical University Budapest, Hungary), Haider, Norbert (University of Vienna), Wobus, Andrea (University of Vienna)   +3 more
core   +1 more source

A Novel MAO-B/SSAO Inhibitor Improves Multiple Aspects of Dystrophic Phenotype in mdx Mice

Antioxidants
Duchenne muscular dystrophy (DMD) is one of the most frequent and severe childhood muscle diseases. Its pathophysiology is multifaceted and still incompletely understood, but we and others have previously shown that oxidative stress plays an important ...
Francesca Gasparella, Leonardo Nogara, Elena Germinario, Lucia Tibaudo, Stefano Ciciliot, Giorgia Piccoli, Francisca Carolina Venegas, Francesca Fontana, Gabriele Sales, Daniele Sabbatini, Jonathan Foot, Wolfgang Jarolimek, Bert Blaauw, Marcella Canton, Libero Vitiello   +14 more
doaj   +1 more source

Thermal dissection of lentil seedling amine oxidase domains by differential scanning calorimetry [PDF]

The relationships between the structural and energetic domains of lentil seedling amine oxidase (LSAO) were investigated using modifiers that target the active site and the carbohydrate moiety of the enzyme.
صبوری, علی اکبر, هاشم نیا, صدیقه, موسوی موحدی, علی اکبر, امانی, مجتبی, فلوریس, جیووانی, احمد, فیضان, مورا, آنا, یوسفی, رضا, موسوی نژاد, سیده زهرا, حکیم الهی, غلامحسین, رضایی طاویرانی, مصطفی   +10 more
core  

The Enhanced Daily Excretion of Urinary Methylamine in Rats Treated with Semicarbazide or Hydralazine May Be Related to the Inhibition of Semicarbazide-sensitive Amine Oxidase Activities

, 1989
The effects of amine oxidase inhibitors upon the daily urinary excretion of monomethylamine (MMA), dimethylamine (DMA), trimethylamine (TMA) and ammonia in the rat have been examined.
S A Mcdougall, G A Lyles
core   +1 more source

Semicarbazide-Sensitive Amine Oxidase Increases in Calcific Aortic Valve Stenosis and Contributes to Valvular Interstitial Cell Calcification. [PDF]

Oxid Med Cell Longev, 2020
Mercier N, Pawelzik SC, Pirault J, Carracedo M, Persson O, Wollensack B, Franco-Cereceda A, Bäck M.   +7 more
europepmc   +1 more source