Anticancer Activity and Safety Profile of Novel 1-(4-Fluorophenoxyacetyl)-4-substituted Thio/Semicarbazide Derivatives [PDF]
Compounds with thiosemicarbazide and semicarbazide scaffolds are among the most promising structures in medicinal chemistry due to the possibility of forming multiple hydrogen bonds.
Paweł Kozyra +7 more
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Progress on the Origin and Formation Mechanism of Semicarbazide in Crustacean Aquatic Products
Nitrofurazone is a synthetic antimicrobial drug developed by the Eaton Institute in the United States in the 1950s. Nitrofurazone can play an inhibitory or bactericidal role by interfering with the glucose metabolism process and oxidase system in ...
Shengjun CHEN +7 more
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Semicarbazide is a newly recognized marine pollutant and has the potential to threaten marine shellfish, the ecological equilibrium and human health.
Lihong Xing +6 more
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A Mechanistic Study on the Non-genotoxic Carcinogenicity of the Food Contaminant Semicarbazide
Semicarbazide was brought to the forefront of scientific discussions by the scientific community in the early 2000’s as the substance was discovered in several food products from both synthetic and natural sources.
Daniel P. Fitzpatrick
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Effects of Sodium Hypochlorite Bleaching on the Quality and Safety of Basa (Pangasius bocourti) Fish Maw: Texture, Collagen Structure, and Semicarbazide Formation [PDF]
This study aimed to investigate the effects of sodium hypochlorite (NaClO) bleaching on the quality of Basa (Pangasius bocourti) fish maw (BFM) and the formation of semicarbazide (SEM).
Honglin Zhang +6 more
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The study was conducted to evaluate the toxicological effects, functional observation battery tests, and sexual maturity of semicarbazide oral gavage administration to juvenile Sprague-Dawley rats for 70 days at 0, 15, 30, and 60 mg/kg/day weaning to ...
Vijaykumar Malashetty +2 more
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Influence of semicarbazide on the peroxidation processes and Lewis carcinoma growth in mice [PDF]
Effects of various doses of semicarbazide on Lewis carcinoma metastasing and peroxidation processes in С57В1 mice have been investigated. In the animals with inoculated Lewis carcinoma, the semicarbazide in the dose of 1/120 LD50 had practical influence ...
L. M. Petrun
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Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue [PDF]
An enzyme hitherto named semicarbazide-sensitive amine oxidase (SSAO), involved in the oxidation of primary amines, is abundantly expressed in adipocytes.
Josep Mercader +3 more
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A Novel Strategy for the Detection of Semicarbazide in Crustaceans by Modified QuEChERS Coupled with Hydrophilic Interaction Liquid Chromatography–Tandem Mass Spectrometry [PDF]
Semicarbazide (SEM), a metabolite of nitrofurazone (NFZ), is widely used to detect the illegal application of NFZ in crustaceans. The conventional detection method involves chemical derivatization combined with reversed-phase liquid chromatography–tandem
Siyuan Wu +6 more
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Hydrogen bonded interaction and synergistic effect on the corrosion protection properties of alkyl benzimidazoles and semicarbazide pair on mild steel in hydrochloric acid at 303, 308 and 313 K have been studied by polarization, electrochemical impedance
K. Ramya +3 more
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