Results 11 to 20 of about 7,328 (210)

A Mechanistic Study on the Non-genotoxic Carcinogenicity of the Food Contaminant Semicarbazide [PDF]

SURE Journal: (Science Undergraduate Research Experience Journal), 2020
Semicarbazide was brought to the forefront of scientific discussions by the scientific community in the early 2000’s as the substance was discovered in several food products from both synthetic and natural sources.
Daniel P. Fitzpatrick
doaj   +2 more sources

Seventy-Day Toxicity Study in Juvenile Sprague-Dawley Rats with Semicarbazide (SEM) from Weaning to Sexual Maturity

Journal of Toxicology, 2022
The study was conducted to evaluate the toxicological effects, functional observation battery tests, and sexual maturity of semicarbazide oral gavage administration to juvenile Sprague-Dawley rats for 70 days at 0, 15, 30, and 60 mg/kg/day weaning to ...
Vijaykumar Malashetty, Raghunandan Deshpande, Somnathreddy Patil   +2 more
doaj   +2 more sources

Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue [PDF]

Journal of Obesity, 2011
An enzyme hitherto named semicarbazide-sensitive amine oxidase (SSAO), involved in the oxidation of primary amines, is abundantly expressed in adipocytes.
Josep Mercader, Zsuzsa Iffiú-Soltész, Sandy Bour, Christian Carpéné   +3 more
doaj   +2 more sources

Influence of semicarbazide on the peroxidation processes and Lewis carcinoma growth in mice [PDF]

The Ukrainian Biochemical Journal, 2014
Effects of various doses of semicarbazide on Lewis carcinoma metastasing and peroxidation processes in С57В1 mice have been investigated. In the animals with inoculated Lewis carcinoma, the semicarbazide in the dose of 1/120 LD50 had practical influence ...
L. M. Petrun
doaj   +2 more sources

Corrosion protection of mild steel in hydrochloric acid solution through the synergistic of alkylbenzimidazoles and semicarbazide pair – Electroanalytical and computational studies

Egyptian Journal of Petroleum, 2017
Hydrogen bonded interaction and synergistic effect on the corrosion protection properties of alkyl benzimidazoles and semicarbazide pair on mild steel in hydrochloric acid at 303, 308 and 313 K have been studied by polarization, electrochemical impedance
K. Ramya, K.K. Anupama, K.M. Shainy, Abraham Joseph   +3 more
doaj   +2 more sources

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives. [PDF]

Chem Biodivers
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Bindra S, Jeong WK, Kabier M, Kumar S, Sudevan ST, Vishwakarma HC, Parambi DGT, Maliyakkal N, Kumar S, Pappachen LK, Kim H, Mathew B.   +11 more
europepmc   +2 more sources

Screening of Chemical Residues and Antimicrobial Resistance in Dehydrated Chicken Feet Intended as Dog Treats: A Pilot Study. [PDF]

Vet Med Int
The pet population is steadily increasing worldwide, and treats, which account for approximately 15% of the pet food market, are the fastest‐growing segment of the pet food industry. However, the widespread use of antimicrobials in poultry farms may pose a direct risk to pets’ health, leading to the emergence of antimicrobial resistance.
Marini C, Lipani F, Sabia C, Nicotra M, Iseppi R, Biscontini G, Cerquetella M, Meschiari M, Gregorio GD, Alagawany M, Tardugno R, Corbo F, Cerbo AD.   +12 more
europepmc   +2 more sources

Automation of the Azapeptide Submonomer Synthesis Method [PDF]

J Pept Sci
The solid phase submonomer azapeptide synthesis method was automated using a commercially available peptide synthesizer. Key findings for the successful automation included the use of stable isocyanate precursor for the semicarbazone installation step, elimination of all cooling steps, use of a heating block, and use of DMF as solvent.
Hobart T, Helton M, Bowles M, Proulx C.
europepmc   +2 more sources

Kinetics study of hydrazodicarbonamide synthesis reaction [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
In this study, the kinetics of hydrazodicarbonamide (HDCA) synthesis reaction was investigated. Hydrazodicarbonamide is prepared by reaction of urea and hydrazine in acidic medium. Synthesis of HDCA from urea and hydrazine is a two steps reaction.
Bakeri Gh., Rahimnejad M.
doaj   +1 more source

Synthesis of 1,6-bis(semicarbazide)hexanes and 1,6-bis(1,2,4-triazol-5-one)hexanes and their antiproliferative and antimicrobial activity [PDF]

Journal of the Serbian Chemical Society, 2012
A series of 1,6-bis(3-substituted-4,5-dihydro-1H-1,2,4-triazol-5-on-4- yl)hexanes (3a-g) were synthesized by the cyclization reaction of 1,6-bis(1- substituted-semicarbazide-4-yl)hexanes (2a-g) in alkaline medium.
Pitucha M., Rzymowska J., Olender A., Grzybowska-Szatkowska L.   +3 more
doaj   +1 more source