Results 61 to 70 of about 9,419 (207)
Singlet oxygen-mediated one-pot chemoselective peptide–peptide ligation [PDF]
, 2017 We here describe a furan oxidation based site-specific chemical ligation approach using unprotected peptide segments. This approach involves two steps: after photooxidation of a furan-containing peptide, ligation is achieved by reaction of the unmasked ...
Antonatou, Eirini +2 more
core +2 more sources
Batch Synthesis of Primaquine Diphosphate Anti‐Malarial Drug
Chemistry – A European Journal, Volume 31, Issue 59, October 22, 2025.According to the WHO, a child under the age of five dies every 2 minutes from malaria in Africa. It is therefore paramount that access and availability of anti‐malarial drugs must be improved. We report a process for the synthesis of Primaquine Diphosphate, where key intermediates were obtained in a much shorter reaction time compared to processes ...
Faith M. Akwi +2 more
wiley +1 more source
Some semicarbazide derivatives and their antimicrobial activity
Communications, Faculty Of Science, University of Ankara Series B Chemistry and Chemical Engineering, 1993 Various semicarbazides and thiosemicarbazides (1-5) and their cyclised products, triazoles, oxadiazoles and thiadiazoles (6-9) have been reported to possess antibacterial, antitubercular and antifungal activities. Based on these findings it w as of interest to prepare some new arylsemicarbazide and arylthiosemicarbazide derivatives and to evaluate ...
F. Abd EL-AZEEM +2 more
openaire +2 more sources
Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core
Asian Journal of Organic Chemistry, Volume 14, Issue 10, October 2025.An efficient method to develop novel dihydropyrido[3,2‐e][1,3]selenazines iminium salts. A comparative study of the key reagent selenourea towards thiourea and urea was carried out to assess the contribution of chalcogen to the pathway. DFT (density functional theory) calculations have predicted the optimized minimum energy structure for the hybrid ...
Reinier Lemos +6 more
wiley +1 more source
ChemistryEurope, Volume 3, Issue 5, September 18, 2025.A pH‐programmable site‐selective cysteine modification in peptides is reported using a triazine–thiol exchange, termed TriTEx. At acidic pH, internal cysteines are targeted while preserving N‐terminal sites; at neutral pH, N‐terminal cysteines are selectively modified via an irreversible S–N shift.
Katerina Gavriel +5 more
wiley +1 more source
Metabolic Effects of Oral Phenelzine Treatment on High-Sucrose-Drinking Mice [PDF]
, 2018 Phenelzine has been suggested to have an antiobesity effect by inhibiting de novo lipogenesis, which led us to investigate the metabolic effects of oral chronic phenelzine treatment in high-sucrose-drinking mice.
Carpéné, Christian +3 more
core +2 more sources
Hazelnut: Explorations toward the Biocatalytic Synthesis of its Aroma Precursor
ChemBioChem, Volume 26, Issue 16, September 12, 2025.This article proposes a biosynthetic route for synthesizing filbertone, the principal flavor compound of hazelnut, through a multienzyme cascade. The pathway uses D‐amino acid oxidase, threonine deaminase, and a regioselective transketolase from Geobacillus stearothermophilus to produce a sustainable, natural hazelnut aroma precursor, addressing ...
Mireia Salvadó‐Pau +3 more
wiley +1 more source
Di-μ-thio-semicarbazide-κS:S-bis-[bis-(thio-semicarbazide-κS)copper(I)] diiodide.
Acta crystallographica. Section E, Structure reports online, 2011 The title compound, [Cu(2){SC(NH(2))NHNH(2)}(6)]I(2), was obtained by the reaction of CuI and thio-semicarbazide (TSCZ) in acetonitrile. Each Cu(I) ion is coordinated by four S atoms of the TSCZ ligands, forming a tetra-hedral geometry. Centrosymmetric dimers are formed by two coordination tetra-hedra sharing a common edge, with a Cu⋯Cu distance of 2 ...
Li, Jia, Shou-Xin, Ma, Da-Cheng, Li
openaire +2 more sources
Reviews in Aquaculture, Volume 17, Issue 4, September 2025.ABSTRACT Nitrofuran metabolites, including semicarbazide, pose significant risks to food safety, particularly in the aquatic industry. Bangladesh's shrimp industry faced major challenges due to nitrofuran contamination, leading to a voluntary export suspension to the European Union (EU).
S. M. Nazmul Alam
wiley +1 more source
Synthesis Optimization of L-Aspartic acid β-hydroxamate by a novel Enzyme, β-Aspartyl-γ-glutamyl transferase [PDF]
, 2015 L-Aspartic acid β-hydroxamate or L-β-Aspartyl hydroxamate (BAH), water soluble- chemical compound currently obtains popularity due to its role in several important biochemical processes and to its bioactivities.
Naohara, Ryosuke +4 more
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