Results 21 to 30 of about 2,335 (166)
Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Lysyl oxidase has emerged as an important enzyme in cancer metastasis. Its activity has been reported to become upregulated in several types of cancer, and blocking its activity has been shown to limit the metastatic potential of various cancers.
Ashley A. Burke +5 more
doaj +1 more source
Review of QSAR Models and Software Tools for Predicting Developmental and Reproductive Toxicity [PDF]
, 2010 This report provides a state-of-the-art review of available computational models for developmental and reproductive toxicity, including Quantitative Structure-Activity Relationship (QSARs) and related estimation methods such as decision tree approaches ...
LO PIPARO ELENA, WORTH Andrew
core +1 more source
The Design and Use of Supramolecular Gels as Crystallisation Media [PDF]
, 2022 The solid-state of pharmaceuticals is a critical area of research for pharmaceuticals companies, primarily due to the impact the solid form can have on the physicochemical properties of a drug.
SMITH, JAMES,PHILIP
core
Transition metal complexes with Girard reagents and their hydrazones [PDF]
, 2012 This is the first review dealing with the coordination chemistry of metal complexes with Girard's reagents and their hydrazones. The short introduction points out to chemical properties and significance of these organic compounds.
Leovac Vukadin M. +3 more
core +1 more source
NEW METAL-CONTAINING POLY(URETHANE-SEMICARBAZIDES) ON THE BASIS OF PYRIDINE DERIVATIVES [PDF]
, 2019 The growth of science and technology of polyurethanes leads to the development of new materials with more desirable properties. Modification of polyurethane (PU) by incorporating metal and functional groups are used extensively to improve various ...
Kositsyna, Olena
core +3 more sources
Čudesna molekula benzotriazol [PDF]
Kemija u Industriji, 2007 In this paper, a review of reactions with benzotriazole as synthetic auxiliary is given. In contrast to most other azoles, benzotriazole reacts with phosgene in molar ratio 1:1 yielding carboxylic acid chloride (BtcCl, 1), which readily reacts with ...
Zorc, B., Butula, I.
doaj
Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds
ChemMedChem, Volume 21, Issue 2, January 2026.Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley +1 more source
Design, synthesis and anticonvulsant activity of some new 5,7-dibromoisatin semicarbazone derivatives [PDF]
, 2013 A series of 5,7-dibromoisatin semicarbazones have been synthesized in good yield, involving aryl urea and aryl semicarbazide formation. The structures of the synthesized compounds were confirmed on the basis of their spectral data. All the compounds were
Kumar, Dheeraj +6 more
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SusMat, Volume 5, Issue 6, December 2025.This review summarizes advances in tin (Sn)‐based perovskite solar cells, a promising lead‐free alternative. It examines the main causes of Voc and fill factor losses, including Sn2+ oxidation, undercoordinated sites, and deep‐level traps. Strategies such as molecular coordination, surface passivation, compositional tuning, interface engineering, and ...
Padmini Pandey +4 more
wiley +1 more source
ChemMedChem, Volume 20, Issue 22, November 18, 2025.A partial proteolysis targeting chimera (PROTAC) library bearing achiral phenyl dihydrouracil cereblon ligands is prepared. It is then applied to the rapid development of a full PROTAC library targeting Bruton's tyrosine kinase, which can be directly used for screening.
Chelsi M. Almodóvar‐Rivera +5 more
wiley +1 more source