Results 171 to 180 of about 32,141 (252)

Loss of p62 Binding Allows TIF-IA Accumulation in Senescence, Which Promotes Phenotypic Changes to Nucleoli and the Senescence Associated Secretory Phenotype. [PDF]

Aging Cell
Thoms HC, Brant TS, Duckett K, Yang Y, Dong J, Wang H, Derby F, Akeke OF, Al-Alayeen F, Newell A, Manasterski P, Gopalakrishnan A, Mann D, Millar FR, Von Kriegsheim A, Acosta JC, Oakley F, Stark LA.   +17 more
europepmc   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma. [PDF]

Oncol Rep
Kitano Y, Miyashita T, Shimasaki T, Makino I, Endo Y, Yamamoto Y, Inaki N, Yagi S.   +7 more
europepmc   +1 more source

Trends in Gestational Diabetes Identified through Universal Screening: A Population‐Based Observational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore trends of gestational diabetes (GDM) prevalence, as well as fasting, 1 h and 2 h post‐load glucose and its determinants in Hungary between 2010 and 2017. Design Cross‐sectional universal screening programme for GDM (3‐point 75 g OGTT at 24–28 weeks of gestation). Setting Tolna County (South‐Western Hungary). Population All
István Panykó, Attila Kun, Gergely Á. Visolyi, Beatrix A. Domján, Márk M. Svébis, Viktória Ferencz, Árpád Kézdi, Tamás Jávorfi, Győző Kocsis, Eszter Szabó, Zsuzsa Kerényi, Ádám G. Tabák   +11 more
wiley   +1 more source

NFATc1 facilitates hepatocellular carcinoma progression by regulating the senescence-associated secretory phenotype. [PDF]

Sci Rep
Chen Z, Huang L, Ding L, Zhang C, Li Y, Wang B, Shi J, Zhang J.   +7 more
europepmc   +1 more source

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing, Xi Chen, Meiyan Jiang, Huiya Fang, Xiaoming Zhu, Xuejing Jin, Yonghui Jiao, Ningning Hou, Weiwei Gong, Aixia Liu   +9 more
wiley   +1 more source

Aging-related, senescence-associated secretory phenotype and allogeneic hematopoietic cell transplantation outcomes in older patients. [PDF]

J Geriatr Oncol
Jeng MY, Wong P, Flynn JR, Ritter E, Ho C, Ruiz JD, Jakubowski AA, Papadopoulos EB, Shaffer BC, Ponce DR, Tamari R, Young JW, Perales MA, Devlin S, Giralt SA, Lin RJ.   +15 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort. [PDF]

Sci Rep
Préfontaine C, Pipella J, Heidinger I, Alcasid N, Thompson PJ.   +4 more
europepmc   +1 more source