Results 221 to 230 of about 492,919 (268)
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Pigment Cell & Melanoma Research, 2020
We all seem to carry at least one mole on our body, those black spots or nevi that may become larger as we grow in childhood but then stay put in size for the rest of our lives, except…. Yes, except if they start growing again, which may give rise to melanoma.
Heinz Arnheiter +1 more
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We all seem to carry at least one mole on our body, those black spots or nevi that may become larger as we grow in childhood but then stay put in size for the rest of our lives, except…. Yes, except if they start growing again, which may give rise to melanoma.
Heinz Arnheiter +1 more
openaire +2 more sources
SATB1, senescence and senescence‐related diseases
Journal of Cellular PhysiologyAbstractAging leads to an accumulation of cellular mutations and damage, increasing the risk of senescence, apoptosis, and malignant transformation. Cellular senescence, which is pivotal in aging, acts as both a guard against cellular transformation and as a check against cancer progression.
Wenjing Qi +4 more
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Nature, 1962
NEEDHAM1 has recently claimed that Minot's paradox2: “Senescence is at its maximum in the very young stages and the rate of senescence diminishes with age”, is false. Instead of the relationship Ṡ = Ġ (where Ṡ = rate of senescence, Ġ = specific growth-rate) indicated by Minot he advocates the use of the relationship Ṡ = k/Ġ in which, however, Ġ refers ...
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NEEDHAM1 has recently claimed that Minot's paradox2: “Senescence is at its maximum in the very young stages and the rate of senescence diminishes with age”, is false. Instead of the relationship Ṡ = Ġ (where Ṡ = rate of senescence, Ġ = specific growth-rate) indicated by Minot he advocates the use of the relationship Ṡ = k/Ġ in which, however, Ġ refers ...
openaire +2 more sources
Nature, 1961
WE owe to Minot1 a startling paradox—the view that the rate of senescence is most rapid at the beginning of life and slowest at the end: to quote the fourth of the laws by which he summarized his conclusions, “Senescence is at its maximum in the very young stages and the rate of senescence diminishes with age”.
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WE owe to Minot1 a startling paradox—the view that the rate of senescence is most rapid at the beginning of life and slowest at the end: to quote the fourth of the laws by which he summarized his conclusions, “Senescence is at its maximum in the very young stages and the rate of senescence diminishes with age”.
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Annual Review of Plant Biology, 2007
Leaf senescence constitutes the final stage of leaf development and is critical for plants’ fitness as nutrient relocation from leaves to reproducing seeds is achieved through this process. Leaf senescence involves a coordinated action at the cellular, tissue, organ, and organism levels under the control of a highly regulated genetic program.
Lim, PO, Kim, HJ, Nam, HG
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Leaf senescence constitutes the final stage of leaf development and is critical for plants’ fitness as nutrient relocation from leaves to reproducing seeds is achieved through this process. Leaf senescence involves a coordinated action at the cellular, tissue, organ, and organism levels under the control of a highly regulated genetic program.
Lim, PO, Kim, HJ, Nam, HG
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British Journal of Dermatology, 1990
The most reliable way to reduce the chronic effects of solar UV radiation is to limit exposure. Animal data using hairless albino mice suggest that the routine use of sunscreens, which usually act as UVB (280-315 nm) filters, may prevent or inhibit skin photocarcinogenesis and photoageing in man.
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The most reliable way to reduce the chronic effects of solar UV radiation is to limit exposure. Animal data using hairless albino mice suggest that the routine use of sunscreens, which usually act as UVB (280-315 nm) filters, may prevent or inhibit skin photocarcinogenesis and photoageing in man.
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CNS & Neurological Disorders - Drug Targets, 2013
In order to understand microglial senescence it is important to also understand neuroinflammation because the distinction between senescent and activated microglia is a fine one to make and not always made easily. Indeed, it is not easy to reliably identify activated microglia which is why we spend some effort here discussing intricacies associated ...
Wolfgang J, Streit, Qing-Shan, Xue
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In order to understand microglial senescence it is important to also understand neuroinflammation because the distinction between senescent and activated microglia is a fine one to make and not always made easily. Indeed, it is not easy to reliably identify activated microglia which is why we spend some effort here discussing intricacies associated ...
Wolfgang J, Streit, Qing-Shan, Xue
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2019
Abstract Senescence is a state of terminal growth arrest, with associated structural and functional changes in the affected cell. Cellular senescence can be induced in embryogenesis and in response to stimuli including aging, DNA damage, and cell stress.
O'Sullivan, Eoin D., Ferenbach, David A.
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Abstract Senescence is a state of terminal growth arrest, with associated structural and functional changes in the affected cell. Cellular senescence can be induced in embryogenesis and in response to stimuli including aging, DNA damage, and cell stress.
O'Sullivan, Eoin D., Ferenbach, David A.
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1984
As the nature of any intrinsic biologic aging process or even of its existence independent of disease is unknown, it is not possible to state whether or not the placenta gets old. As term approaches, the placenta accumulates a variety of lesions which seem pathological.
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As the nature of any intrinsic biologic aging process or even of its existence independent of disease is unknown, it is not possible to state whether or not the placenta gets old. As term approaches, the placenta accumulates a variety of lesions which seem pathological.
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American Journal of Hematology, 1981
AbstractA study of 196 healthy geriatric females and 26 males confirmed the high prevalence of anemia in this population. Forty‐two females (21.4%) had a hematocrit of less than 36% and nine (34%) of the males had a value of less than 40%. A careful evaluation, including a therapeutic trial of oral iron in some subjects, made a diagnosis of iron ...
D A, Lipschitz +2 more
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AbstractA study of 196 healthy geriatric females and 26 males confirmed the high prevalence of anemia in this population. Forty‐two females (21.4%) had a hematocrit of less than 36% and nine (34%) of the males had a value of less than 40%. A careful evaluation, including a therapeutic trial of oral iron in some subjects, made a diagnosis of iron ...
D A, Lipschitz +2 more
openaire +2 more sources