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Correction to "AMPK-Upregulated microRNA-708 Plays as a Suppressor of Cellular Senescence and Aging Via Downregulating Disabled-2 and mTORC1 Activation". [PDF]
MedComm (2020)europepmc +1 more source
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2021
Researchers are now beginning to unravel the variation in patterns of whole-organism senescence across the tree of life, yet the existence of senescence in nature itself is an evolutionary conundrum. This document introduces the literature on explanations for whole-organism senescence, starting with the early classical theories developed in the 20th ...
Mina Bayanati +2 more
+5 more sources
Researchers are now beginning to unravel the variation in patterns of whole-organism senescence across the tree of life, yet the existence of senescence in nature itself is an evolutionary conundrum. This document introduces the literature on explanations for whole-organism senescence, starting with the early classical theories developed in the 20th ...
Mina Bayanati +2 more
+5 more sources
CNS & Neurological Disorders - Drug Targets, 2013
In order to understand microglial senescence it is important to also understand neuroinflammation because the distinction between senescent and activated microglia is a fine one to make and not always made easily. Indeed, it is not easy to reliably identify activated microglia which is why we spend some effort here discussing intricacies associated ...
Wolfgang J, Streit, Qing-Shan, Xue
openaire +2 more sources
In order to understand microglial senescence it is important to also understand neuroinflammation because the distinction between senescent and activated microglia is a fine one to make and not always made easily. Indeed, it is not easy to reliably identify activated microglia which is why we spend some effort here discussing intricacies associated ...
Wolfgang J, Streit, Qing-Shan, Xue
openaire +2 more sources
Annual Review of Plant Biology, 2007
Leaf senescence constitutes the final stage of leaf development and is critical for plants’ fitness as nutrient relocation from leaves to reproducing seeds is achieved through this process. Leaf senescence involves a coordinated action at the cellular, tissue, organ, and organism levels under the control of a highly regulated genetic program.
Lim, PO, Kim, HJ, Nam, HG
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Leaf senescence constitutes the final stage of leaf development and is critical for plants’ fitness as nutrient relocation from leaves to reproducing seeds is achieved through this process. Leaf senescence involves a coordinated action at the cellular, tissue, organ, and organism levels under the control of a highly regulated genetic program.
Lim, PO, Kim, HJ, Nam, HG
openaire +3 more sources
Trends in Cognitive Sciences, 2017
The brain during healthy aging exhibits gradual deterioration of structure but maintains a high level of cognitive ability. These structural changes are often accompanied by reorganization of functional brain networks. Existing neurocognitive theories of aging have argued that such changes are either beneficial or detrimental.
Naik, S. +4 more
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The brain during healthy aging exhibits gradual deterioration of structure but maintains a high level of cognitive ability. These structural changes are often accompanied by reorganization of functional brain networks. Existing neurocognitive theories of aging have argued that such changes are either beneficial or detrimental.
Naik, S. +4 more
openaire +3 more sources
Trends in Ecology & Evolution, 1992
Senescence is defined by evolutionary biologists as the decline in age-specific survival and fecundity that reflects declines in the performance of many different physiological functions in individuals of sufficiently advanced age. Senescence is widely recognized to occur among plants with a single reproductive event, but the extent to which senescence
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Senescence is defined by evolutionary biologists as the decline in age-specific survival and fecundity that reflects declines in the performance of many different physiological functions in individuals of sufficiently advanced age. Senescence is widely recognized to occur among plants with a single reproductive event, but the extent to which senescence
openaire +2 more sources
1984
As the nature of any intrinsic biologic aging process or even of its existence independent of disease is unknown, it is not possible to state whether or not the placenta gets old. As term approaches, the placenta accumulates a variety of lesions which seem pathological.
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As the nature of any intrinsic biologic aging process or even of its existence independent of disease is unknown, it is not possible to state whether or not the placenta gets old. As term approaches, the placenta accumulates a variety of lesions which seem pathological.
openaire +2 more sources