Results 251 to 260 of about 112,157 (308)

Signaling networks in cancer stromal senescent cells establish malignant microenvironment. [PDF]

Proc Natl Acad Sci U S A
Zhang Y, Wang TW, Tamatani M, Zeng X, Nakamura L, Omori S, Yamaguchi K, Hatakeyama S, Shimizu E, Yamazaki S, Furukawa Y, Imoto S, Johmura Y, Nakanishi M.   +13 more
europepmc   +1 more source

Injectable Senolytic Hydrogel Depot for the Clearance of Senescent Cells. [PDF]

Biomacromolecules
Garau Paganella L, Bovone G, Cuni F, Labouesse C, Cui Y, Giampietro C, Tibbitt MW.   +6 more
europepmc   +1 more source

SMARCA4 regulates the NK-mediated killing of senescent cells. [PDF]

Sci Adv
Reen V, D'Ambrosio M, Søgaard PP, Tyson K, Leeke BJ, Clément I, Dye ICA, Pombo J, Kuba A, Lan Y, Burr J, Bomann IC, Kalyva M, Birch J, Khadayate S, Young G, Provencher D, Mes-Masson AM, Vernia S, McGranahan N, Brady HJM, Rodier F, Nativio R, Percharde M, McNeish IA, Gil J.   +25 more
europepmc   +1 more source

Could senescent cells be the prescription for therapeutic cancer vaccines? [PDF]

Immunotherapy
Liu Y, Kron SJ.
europepmc   +1 more source

Correction to 'Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data'. [PDF]

Nucleic Acids Res
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Senescent cells support limb regeneration

Nature Reviews Molecular Cell Biology, 2023
openaire   +4 more sources

T cell senescence

Frontiers in Bioscience, 2001
The aging of the immune system, referred to as immunosenescence, is associated with a dramatic reduction in responsiveness as well as functional dysregulation. This deterioration of immune function with advancing age contributes to the increased incidence among the elderly of morbidity and mortality from infectious disease, and possibly autoimmunity ...
P, Linton, M L, Thoman
openaire   +2 more sources

Endothelial Cell Senescence

2006
The wear and tear processes that are thought to contribute to human ageing may play an important role in the development of vascular diseases. One such process is cellular senescence. In endothelial cells the senescent phenotype can be induced by a number of factors, including telomere damage, oxidative stress and sustained mitogenic stimulation ...
J D, Erusalimsky, D J, Kurz
openaire   +2 more sources

Cell senescence and cancer

Nature Reviews Cancer, 2001
Historically, the senescent state has been associated with, and was named after, the cell-cycle arrest that occurs after cells have undergone an intrinsically defined number of divisions in vitro. More recently, however, it has been shown that extrinsic factors, including those encountered in normal tissue-culture environments, can prematurely induce ...
N F, Mathon, A C, Lloyd
openaire   +2 more sources