Results 281 to 290 of about 12,101,411 (341)

Cell surface ATP6V1B2 marks a subset of persistent senescent cells with increased resistance to apoptosis

Freizus N, Majewska J, Ovadya Y, Kopitman E, Porat Z, Mayo A, Meir-Salame T, Dassa B, Stelzer G, Alon U, Krizhanovsky V.   +10 more
europepmc   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro-Inflammatory Phenotype of Senescent Cells. [PDF]

Aging Cell
Jiang B, Zhang H, Xu Q, Jiang Z, He R, Fu Q, Sun Y.   +6 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Senescent cells promote viral infection-associated inflammation and tissue damage through a robust NF-κB pathway. [PDF]

Cell Commun Signal
Tian M, Ma J, Li Z, Ye C, Cui X, Wang G, Liu S, Qudus MS, Afaq U, Fan H, Xiong J, Li G, Luo C, Wang Z, Jin Z, Guo M, Wang X, Huang Z, Zheng F, Wu K, Zhu C.   +20 more
europepmc   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Coming of age: could obesity-related metabolic complications be treated by targeting senescent cells? [PDF]

Front Cell Dev Biol
Kasperova BJ, Cinkajzlova A, Horvath L, Svoboda P, Haluzik M, Stemberkova Hubackova S.   +5 more
europepmc   +1 more source

Targeting senescent cells for the treatment of age-associated diseases. [PDF]

J Biochem
Suda M, Tchkonia T, Kirkland JL, Minamino T.   +3 more
europepmc   +1 more source

<i>Lactiplantibacillus plantarum</i>OLL2712 Protects From the Intestinal Dysfunction in D-Galactose Induced Senescent Cells. [PDF]

Food Sci Nutr
Watanabe-Yasuoka Y, Watanabe R, Gotou A, Nakajima-Adachi H, Hachimura S, Sashihara T.   +5 more
europepmc   +1 more source

Persistent accumulation of therapy-induced senescent cells: an obstacle to long-term cancer treatment efficacy. [PDF]

Int J Oral Sci
Luo J, Sun T, Liu Z, Liu Y, Liu J, Wang S, Shi X, Zhou H.   +7 more
europepmc   +1 more source

Senescent Cells: An Emerging Therapeutic Target for Hemodialysis Fistula Maturation. [PDF]

Kidney360
Vazquez-Padron RI, Vazquez-Padron RI, Shiu YT.   +2 more
europepmc   +1 more source