Results 141 to 150 of about 2,081 (185)
Clinical, Cosmetic and Investigational DermatologyHuilan Zheng,1 Jingping Wu,2 Jinhong Feng,2 Hongbin Cheng3 1School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, 610075, People’s Republic of China; 2Department of Medical Cosmetology, Hospital of ...
Zheng H, Wu J, Feng J, Cheng H
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Moving senolytics closer to the clinic in IPF
eBioMedicine, 2023 Daniel Kramer +2 more
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Bcl-2 inhibitors as senolytic agents: a systematic review of in vitro evidence (Final Draft)
This project aims to systematically review the current evidence on Bcl-2 family inhibitors and their senolytic potential on in vitro models of cellular senescence.
Victor Juan de Souza Lima
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Editorial: Immunosenescence in organ transplantation
Frontiers in TransplantationJasper Iske +5 more
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Editorial: Women in aging and the immune system
Frontiers in AgingJenna M. Bartley, Anshu Agrawal
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Senolytic Therapy for Cerebral Ischemia-Reperfusion Injury
International Journal of Molecular Sciences, 2021 Ischemic stroke is one of the leading causes of death, and even timely treatment can result in severe disabilities. Reperfusion of the ischemic stroke region and restoration of the blood supply often lead to a series of cellular and biochemical ...
Kim Byung-Soo +2 more
exaly +2 more sources
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The potential of Senolytics in transplantation
Mechanisms of Ageing and Development, 2021Older organs provide a substantial unrealized potential with the capacity to close the gap between demand and supply in organ transplantation. The potential of senolytics in improving age-related conditions has been shown in various experimental studies and early clinical trials. Those encouraging data may also be of relevance for transplantation.
Tomohisa Matsunaga +5 more
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Advanced Healthcare Materials, 2022 Intervertebral disc (IVD) degeneration (IVDD) is a leading cause of chronic low back pain. There is a strong clinical demand for more effective treatments for IVDD as conventional treatments provide only symptomatic relief rather than arresting IVDD ...
Kim Byung-Soo, Ju-Ro Lee, Mungyo Jung
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Obesity, Senescence, and Senolytics
2021Obesity is a major risk factor for the development of comorbidities such as type 2 diabetes, neurodegenerative disorders, osteoarthritis, cancer, cardiovascular and renal diseases. The onset of obesity is linked to an increase of senescent cells within adipose tissue and other organs.
Selim, Chaib +2 more
openaire +2 more sources