Results 161 to 170 of about 8,908 (223)

Protodioscin enhances Methotrexate-induced senescence and senolytic activity in HepG2 liver cancer spheroids by modulating cell cycle regulators and the TGF-β/p-Smad2-4 signaling pathway. [PDF]

Sci Rep
Jafaei Souq A, Ghanbari A, Tabandeh MR, Zamir Nasta T, Faramarzi A, Makalani F, Jalili C.   +6 more
europepmc   +1 more source

Harnessing the NKG2D immune surveillance pathway using engineered T-cells for the treatment of human disease. [PDF]

Hum Vaccin Immunother
Glover M, Maher J, Davies DM.
europepmc   +1 more source

Cellular senescence mediates doxorubicin chemotherapy-induced vascular endothelial dysfunction: translational evidence of prevention with senolytic treatment. [PDF]

Am J Physiol Heart Circ Physiol
Venkatasubramanian R, Mahoney SA, Hutton DA, VanDongen NS, Brunt VE, Greenberg NT, Longtine AG, Brandt L, Beyer AM, Melov S, Rossman MJ, Seals DR, Clayton ZS.   +12 more
europepmc   +1 more source

Viability of <i>Dugesia dorotocephala</i> Planaria with the Senolytic Drug ARV-825. [PDF]

MicroPubl Biol
Wells A, Munroe WH.
europepmc   +1 more source

Senolytic-loaded asymmetric wound dressing for targeted senescent cell clearance in diabetic wound healing. [PDF]

Mater Today Bio
Zhang M, Wang Y, Dai Y, Hu Y, Fu W, Zhao Y, Ma H, Zhang D, Chen Y, Zhou Y, Du L, Chang J, Liu F, Chen S, Wang F, Xiao D, Li Z.   +16 more
europepmc   +1 more source

Cytotoxic and senescence-inducing effects of BLU554 in pancreatic ductal adenocarcinoma: an in vitro study. [PDF]

BMC Cancer
Fujiwara M, Shinji S, Shichi Y, Nonaka K, Hasegawa Y, Takahashi K, Rokutan H, Arai T, Ishiwata T.   +8 more
europepmc   +1 more source

Senolytic Treatment Improves Responsiveness to Mechanical Loading in the Skeleton of Aged Mice. [PDF]

Int J Mol Sci
Cunningham CJ, Kok HJ, Farr JN, Khosla S, Robling AG.   +4 more
europepmc   +1 more source

Senolytics: The Modern Snake Oil? [PDF]

The Journal of nutrition, health and aging, 2019
openaire   +2 more sources

Editorial: Immunosenescence in organ transplantation

Frontiers in Transplantation
Jasper Iske, Jasper Iske, Jasper Iske, Jasper Iske, Jasper Iske, Hao Zhou   +5 more
doaj   +1 more source

Towards a personalized approach in senolytic trials. [PDF]

Nat Aging
Khosla S, Monroe DG, Farr JN.
europepmc   +1 more source