Results 21 to 30 of about 18,846 (144)
Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ
eLife, 2021 Transmembrane signaling proteins couple extracytosolic sensors to cytosolic effectors. Here, we examine how binding of Mg2+ to the sensor domain of an E. coli two component histidine kinase (HK), PhoQ, modulates its cytoplasmic kinase domain.
Bruk Mensa +5 more
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Architecture of a complete Bce-type antimicrobial peptide resistance module
Nature Communications, 2023 Gram-positive bacteria synthesize and secrete antimicrobial peptides that target the essential process of peptidoglycan synthesis. These antimicrobial peptides not only regulate the dynamics of microbial communities but are also of clinical importance as
Natasha L. George, Benjamin J. Orlando
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Novel Family of Sensor Histidine Kinase Genes in Arabidopsis thaliana [PDF]
Plant and Cell Physiology, 2001 We identified three novel, highly homologous, sensor histidine kinases that possibly function in the plasma membrane of Arabidopsis thaliana, i.e. AHK2, 3 and 4. While AHK2 and 3 are expressed in several organs, AHK4 is mainly expressed in roots. AHK3 suppresses a sensor histidine kinase mutant of yeast.
C, Ueguchi +3 more
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Structure of the entire cytoplasmic portion of a sensor histidine‐kinase protein [PDF]
The EMBO Journal, 2005 The large majority of histidine kinases (HKs) are multifunctional enzymes having autokinase, phosphotransfer and phosphatase activities, and most of these are transmembrane sensor proteins. Sensor HKs possess conserved cytoplasmic phosphorylation and ATP-binding kinase domains.
Alberto, Marina +2 more
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Feedback Control of a Two-Component Signaling System by an Fe-S-Binding Receiver Domain
mBio, 2020 Two-component signaling systems (TCSs) function to detect environmental cues and transduce this information into a change in transcription. In its simplest form, TCS-dependent regulation of transcription entails phosphoryl-transfer from a sensory ...
Benjamin J. Stein +2 more
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Journal of Fungi, 2021 Different external stimuli are perceived by multiple sensor histidine kinases and transmitted by phosphorylation via the phosphotransfer protein Ypd1p in the multistep phosphorelay system of the high osmolarity glycerol signaling pathway of filamentous ...
Sri Bühring +4 more
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Role of a sensor histidine kinase ChiS of Vibrio cholerae in pathogenesis [PDF]
International Journal of Medical Microbiology, 2016 Vibrio cholera survival in an aquatic environment depends on chitin utilization pathway that requires two factors, chitin binding protein and chitinases. The chitinases and the chitin utilization pathway are regulated by a two-component sensor histidine kinase ChiS in V. cholerae.
Chourashi, Rhishita +6 more
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A novel two-component system involved in the transition to secondary metabolism in Streptomyces coelicolor. [PDF]
PLoS ONE, 2012 BACKGROUND: Bacterial two-component signal transduction regulatory systems are the major set of signalling proteins frequently mediating responses to changes in the environment.
Daniel Rozas +2 more
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Structure and function of HWE/HisKA2-family sensor histidine kinases [PDF]
Current Opinion in Microbiology, 2017 Sensor histidine kinases regulate adaptive cellular responses to changes in the chemical or physical state of the environment. HWE/HisKA2-family kinases comprise a subset of histidine kinases that is defined by unique sequence motifs in both the catalytic and non-catalytic regions.
Julien, Herrou +2 more
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FEBS Open Bio, 2014 Two-component signal transduction systems (TCS), consisting of a sensor histidine protein kinase and its cognate response regulator, are an important mode of environmental sensing in bacteria.
Alisha Dhiman +3 more
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